ANTI-AMYLOID, BETA- (1-40), HUMAN

Product Name
ANTI-AMYLOID, BETA- (1-40), HUMAN
Chemical Name
ANTI-AMYLOID, BETA- (1-40), HUMAN
Synonyms
ANTI-AMYLOID, BETA 1-40;ANTI-BETA-AMYLOID PEPTIDE;ANTI-HUMAN AMYLOID BETA [1-40];ANTI-BETA-AMYLOID (1-40), HUMAN;ANTI-BETA-AMYLOID [1-40] (AB-1);ANTI-AMYLOID BETA-PROTEIN (1-40);ANTI-AMYLOID, BETA- (1-40), HUMAN;ANTI-BETA-AMYLOID (1-40) RABBIT PAB;RABBIT ANTI-HUMAN AMYLOID BETA [1-40];ANTI-AMYLOID BETA-PROTEIN (HUMAN, 1-40)
CBNumber
CB6262880
Formula Weight
0
MOL File
Mol file
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ANTI-AMYLOID, BETA- (1-40), HUMAN Property

storage temp. 
−20°C
form 
liquid
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A8326
Product name
Anti-β-Amyloid Protein (1-40) antibody produced in rabbit
Purity
whole antiserum
Packaging
0.5ML
Price
$518.4
Updated
2024/03/01
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ANTI-AMYLOID, BETA- (1-40), HUMAN Chemical Properties,Usage,Production

Uses

Anti-β-Amyloid Protein (1-40) antibody produced in rabbit has been used in:

  • immunocytochemical localization of Aβ peptides
  • immunocytochemistry
  • immunoprecipitation
  • focused ultrasound-microbubble enhanced antibody delivery (FUS-MB)

General Description

Amyloid precursor proteins (APPs) are members of a large family of 70 kDa transmembrane glycoproteins that are found in a wide range of tissues. APP is expressed in the brain. It is located on human chromosome 21. APPs have three main isoforms, namely, APP695, APP751 and APP770, that are derived from alternative splicing events in cells.

Biochem/physiol Actions

The β-amyloid precursor protein (APP) is cleaved sequentially by the proteolytic enzymes β-secretase (BACE1) and γ-secretase to produce β-amyloid (Aβ) peptides with the Aβ1-42 and the Aβ1-40 forms being the most prevalent. Secreted Aβ peptides are degraded either via a re-uptake mechanism followed by endosomal degradation, or by an extracellular insulin degrading enzyme. Extracellular accumulation of Aβ leads to the formation of aggregates, fibrils and eventually amyloid deposits called neuritic plaques, which is the hallmark of Alzheimer′s disease (AD).Rabbit Anti-β-Amyloid Protein (1-40) antibody does not stain control sections of normal brain tissues.

ANTI-AMYLOID, BETA- (1-40), HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

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ANTI-AMYLOID, BETA- (1-40), HUMAN Suppliers

Germany 1 Japan 2 Switzerland 2 United Kingdom 1 United States 5 Global 11
Riedel-de Haen AG
Tel
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Country
United States
ProdList
6773
Advantage
87
SIGMA-RBI
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Switzerland
ProdList
6896
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91
Alexis Corporation
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Email
alexis-ch@alexis-corp.ch
Country
Switzerland
ProdList
3599
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74
Kanto Chemical Co., Inc.
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Email
reag-info@gms.kanto.co.jp
Country
Japan
ProdList
6756
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74
Peptide Institute, Inc.
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Email
info@peptide.co.jp
Country
Japan
ProdList
992
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70
Chemicon Internatinal, Inc.
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custserv@chemicon.com
Country
United States
ProdList
4175
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65
EMD Biosciences, Inc.
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technical@calbiochem.com
Country
United States
ProdList
6529
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66
VWR International
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solutions@vwr.com
Country
United Kingdom
ProdList
6548
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82
BIOTREND Chemikalien GmbH
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Email
jaeger@biotrend.com
Country
Germany
ProdList
6115
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76
Zymed Laboratories Inc.
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Country
United States
ProdList
3068
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86

ANTI-AMYLOID, BETA- (1-40), HUMANRelated Search:


  • Anti-β-Amyloid Protein (1-40) antibody produced in rabbit
  • BETA-AMYLOID (1-40) (AB-1) POLYCLONAL ANTIBODY
  • ANTI-HUMAN AMYLOID BETA [1-40]
  • ANTI-AMYLOID BETA-PROTEIN (1-40)
  • ANTI-AMYLOID BETA-PROTEIN (1-40)-CLONE OM16
  • ANTI AMYLOID BETA PROTEIN (1-40) (HUMAN)
  • ANTI-AMYLOID BETA-PROTEIN (HUMAN, 1-40)
  • ANTI-AMYLOID, BETA 1-40
  • ANTI-AMYLOID, BETA- (1-40), HUMAN
  • ANTI-BETA-AMYLOID [1-40] (AB-1)
  • ANTI-BETA-AMYLOID (1-40), HUMAN
  • ANTI-BETA-AMYLOID (1-40) RABBIT PAB
  • ANTI-BETA-AMYLOID PEPTIDE
  • ANTI-BETA-AMYLOID PEPTIDE (1-40) (HUMAN)
  • RABBIT ANTI-HUMAN AMYLOID BETA [1-40]
  • AM-AZAntibodies for Neurobiology
  • Antibodies for Alzheimer and Neurodegenerative Disease Research
  • Antibodies for Neurodegenerative Diseases Research
  • Alphabetical Index
  • Antibodies