4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester
- Product Name
- 4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester
- CAS No.
- 39497-01-3
- Chemical Name
- 4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester
- Synonyms
- 2-hydroxy-4-carbomethoxyquinoline;Methyl 2-Oxo-1H-quinoline-4-carboxylate;Methyl 2-oxo-1,2-dihydroquinoline-4-carboxylate;4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester;Methyl 2-oxo-1,2-dihydroquinoline-4-carboxylate, 97%, QE-2343
- CBNumber
- CB62639361
- Molecular Formula
- C11H9NO3
- Formula Weight
- 203.19
- MOL File
- 39497-01-3.mol
4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester Property
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- White to light brown Solid
- InChI
- InChI=1S/C11H9NO3/c1-15-11(14)8-6-10(13)12-9-5-3-2-4-7(8)9/h2-6H,1H3,(H,12,13)
- InChIKey
- VVZNRIXRLYHAKG-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=CC=C2)C(C(OC)=O)=CC1=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B496065
- Product name
- Methyl2-Oxo-1H-quinoline-4-carboxylate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-0039009
- Product name
- Methyl2-oxo-1,2-dihydroquinoline-4-carboxylate
- Packaging
- 5g
- Price
- $70
- Updated
- 2021/12/16
- Product number
- CS-0039009
- Product name
- Methyl2-oxo-1,2-dihydroquinoline-4-carboxylate
- Packaging
- 10g
- Price
- $116
- Updated
- 2021/12/16
- Product number
- CM143081
- Product name
- methyl2-oxo-1,2-dihydroquinoline-4-carboxylate
- Purity
- 95%
- Packaging
- 10g
- Price
- $143
- Updated
- 2021/12/16
- Product number
- CM143081
- Product name
- methyl2-oxo-1,2-dihydroquinoline-4-carboxylate
- Purity
- 95%
- Packaging
- 25g
- Price
- $262
- Updated
- 2021/12/16
4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester Chemical Properties,Usage,Production
Synthesis
67-56-1
15733-89-8
39497-01-3
Example II Synthesis of 2-quinoline triazole derivatives: 2-hydroxyquinoline-4-carboxylic acid (500 mg, 2.65 mmol) was suspended in anhydrous methanol and concentrated sulfuric acid (96%, 40 drops) was added slowly. The reaction mixture was heated to reflux until the solution became clear. Stirring was continued under reflux conditions for 18 hours (the reaction was monitored by LC-MS until the starting material disappeared completely). Upon completion of the reaction, it was cooled to room temperature and a white precipitate was precipitated. The precipitate was collected by filtration and washed with diethyl ether to give a white solid product in 70% yield (0.38 g). The product was characterized by 1H NMR (DMSO, INOVA-400): δ 3.91 (s, 3H), 6.88 (d, 1H, J = 1.6 Hz), 7.22 (td, 1H, Jt = 7.5 Hz, 0.8 Hz), 7.35 (d, 1H, J = 8.4 Hz), 7.55 (td, 1H, Jt = 7.2 Hz).
References
[1] Patent: WO2012/6068, 2012, A2. Location in patent: Page/Page column 64-65
[2] Patent: WO2006/66584, 2006, A1. Location in patent: Page/Page column 19
[3] Chemistry - A European Journal, 2009, vol. 15, # 24, p. 5950 - 5955
[4] Patent: WO2007/9250, 2007, A1. Location in patent: Page/Page column 40
4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester Suppliers
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