ChemicalBook > CAS DataBase List > Methyl 5-(broMoMethyl)-2-fluorobenzoate

Methyl 5-(broMoMethyl)-2-fluorobenzoate

Product Name
Methyl 5-(broMoMethyl)-2-fluorobenzoate
CAS No.
709-45-5
Chemical Name
Methyl 5-(broMoMethyl)-2-fluorobenzoate
Synonyms
Methyl 5-(broMoMethyl)-2-fluorobenzoate;5-Bromomethyl-2-fluoro-benzoic acid methyl ester;5-(bromomethyl)-2-fluoro-methylester benzoic acid;Benzoic acid, 5-(bromomethyl)-2-fluoro-, methyl ester
CBNumber
CB62648514
Molecular Formula
C9H8BrFO2
Formula Weight
247.06
MOL File
709-45-5.mol
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Methyl 5-(broMoMethyl)-2-fluorobenzoate Property

Boiling point:
304.0±37.0 °C(Predicted)
Density 
1.534±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
Appearance
White to off-white Solid
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

SynQuest Laboratories
Product number
2723-B-22
Product name
Methyl 5-(bromomethyl)-2-fluorobenzoate
Purity
95%
Packaging
250mg
Price
$202
Updated
2021/12/16
AK Scientific
Product number
4457DA
Product name
Methyl5-(bromomethyl)-2-fluorobenzoate
Packaging
1g
Price
$321
Updated
2021/12/16
Ambeed
Product number
A192839
Product name
Methyl5-(bromomethyl)-2-fluorobenzoate
Purity
95%
Packaging
100mg
Price
$50
Updated
2021/12/16
Aaron Chemicals
Product number
AR005QQ2
Product name
Benzoicacid,5-(bromomethyl)-2-fluoro-,methylester
Purity
95%
Packaging
100mg
Price
$56
Updated
2021/12/16
Ambeed
Product number
A192839
Product name
Methyl5-(bromomethyl)-2-fluorobenzoate
Purity
95%
Packaging
250mg
Price
$77
Updated
2021/12/16
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Methyl 5-(broMoMethyl)-2-fluorobenzoate Chemical Properties,Usage,Production

Synthesis

816449-70-4

709-45-5

Preparation of methyl 5-(bromomethyl)-2-fluorobenzoate (3): methyl 2-fluoro-5-(hydroxymethyl)benzoate (2) (5 g, 27.17 mmol, 1 eq.) was dissolved in anhydrous dichloromethane (50 mL) followed by addition of phosphorus tribromide (2.19 g, 8.12 mmol, 0.3 eq.). The reaction mixture was stirred at room temperature for 3 hours. Upon completion of the reaction, the reaction was quenched with saturated sodium bicarbonate solution and extracted with dichloromethane (3 x 100 mL). The organic phases were combined, washed sequentially with water (3 x 30 mL) and brine (1 x 30 mL), dried over anhydrous sodium sulfate, filtered and concentrated to afford methyl 5-(bromomethyl)-2-fluorobenzoate (3) (4.8 g, 71% yield) as an off-white solid.

References

[1] Patent: WO2016/16316, 2016, A1. Location in patent: Page/Page column 226; 227; 354; 355

Methyl 5-(broMoMethyl)-2-fluorobenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 5-(broMoMethyl)-2-fluorobenzoate Suppliers

shanghai aokchem co., ltd
Tel
021-68712331 39130253
Fax
18621350903
Email
aokchem@gmail.com
Country
China
ProdList
332
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Shanghai Leto Pharmatech Co.,Ltd.
Tel
18016401466
Fax
QQ: 1375988926
Email
sales@letopharm.com
Country
China
ProdList
245
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
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60
Shanghai ChuangYan Chemical Technology Co., Ltd.
Tel
021-11111111 11111111111
Fax
qq:546919421
Email
546919421@qq.com
Country
China
ProdList
3526
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55
ShangHai AmK Pharmaceutical Technology Co., Ltd.
Tel
微信 17321281695 18019252918
Fax
17321281695
Email
sale@amkchem.com
Country
China
ProdList
15136
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SanoChem (Chengdu) Tech. Co., Ltd.
Tel
28-87999436 02887999436
Fax
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Country
China
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SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
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Fax
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China
ProdList
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Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
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China
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131957
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Dezhou LonWel Pharmaceutical Technology Co., Ltd.
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13761310616
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China
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Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
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info@amateksci.com
Country
China
ProdList
28785
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709-45-5, Methyl 5-(broMoMethyl)-2-fluorobenzoateRelated Search:


  • Methyl 5-(broMoMethyl)-2-fluorobenzoate
  • 5-Bromomethyl-2-fluoro-benzoic acid methyl ester
  • 5-(bromomethyl)-2-fluoro-methylester benzoic acid
  • Benzoic acid, 5-(bromomethyl)-2-fluoro-, methyl ester
  • 709-45-5