ChemicalBook > CAS DataBase List > AZD2461

AZD2461

Product Name
AZD2461
CAS No.
1174043-16-3
Chemical Name
AZD2461
Synonyms
CS-739;AZD2461;AZD 2461, >=98%;AZD2461 AZD-2461;AZD2461 USP/EP/BP;4-(4-Fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one;4-[4-Fluoro-3-[(4-methoxypiperidin-1-yl)carbonyl]benzyl]phthalazin-1(2H)-one;4-[[4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one;4-[[4-Fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-1(2H)-phthalazinone;1(2H)-Phthalazinone, 4-[[4-fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-
CBNumber
CB62655394
Molecular Formula
C22H22FN3O3
Formula Weight
395.43
MOL File
1174043-16-3.mol
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AZD2461 Property

Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
insoluble in H2O; ≥16.35 mg/mL in DMSO; ≥45.2 mg/mL in EtOH with ultrasonic
form 
powder
pka
12.07±0.40(Predicted)
color 
white to beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P314Get medical advice/attention if you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1858
Product name
AZD2461
Purity
≥98% (HPLC)
Packaging
5MG
Price
$102
Updated
2023/06/20
Sigma-Aldrich
Product number
SML1858
Product name
AZD2461
Purity
≥98% (HPLC)
Packaging
25MG
Price
$413
Updated
2023/06/20
Cayman Chemical
Product number
16876
Product name
AZD 2461
Purity
≥95%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
16876
Product name
AZD 2461
Purity
≥95%
Packaging
5mg
Price
$183
Updated
2024/03/01
Cayman Chemical
Product number
16876
Product name
AZD 2461
Purity
≥95%
Packaging
10mg
Price
$341
Updated
2024/03/01
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AZD2461 Chemical Properties,Usage,Production

Uses

4-[4-Fluoro-3-[(4-methoxypiperidin-1-yl)carbonyl]benzyl]phthalazin-1(2H)-one is a phthalazinone derivative and potential PARP inhibitor.

Biochem/physiol Actions

AZD2461, an olaparib analog, is an orally available, potent and selective PARP1 and PARP2 inhibitor that is a poor substrate for drug transporters. AZD2461 exhibits a high efficacy in olaparib-resistant tumors that overexpress P-glycoprotein.

storage

Store at -20°C

AZD2461 Preparation Products And Raw materials

Raw materials

Preparation Products

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AZD2461 Suppliers

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View Lastest Price from AZD2461 manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
AZD2461 1174043-16-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-13
Career Henan Chemical Co
Product
AZD2461 1174043-16-3
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-01-29

1174043-16-3, AZD2461Related Search:

FLURBIPROFEN AXETIL Nintedanib SB525334 Veliparib Rapamycin PLX4032 Olaparib

  • 4-[[4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one
  • 4-[[4-Fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-1(2H)-phthalazinone
  • CS-739
  • AZD2461
  • 4-[4-Fluoro-3-[(4-methoxypiperidin-1-yl)carbonyl]benzyl]phthalazin-1(2H)-one
  • 1(2H)-Phthalazinone, 4-[[4-fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-
  • AZD 2461, >=98%
  • AZD2461 USP/EP/BP
  • 4-(4-Fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
  • AZD2461 AZD-2461
  • 1174043-16-3
  • Inhibitors
  • Inhibitor