ChemicalBook > CAS DataBase List > (4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate

(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate

Product Name
(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate
CAS No.
196085-84-4
Chemical Name
(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate
Synonyms
Atorvastatin Impurity Z;Atorvastatin Impurity 61;Atorvastatin calcium impurity 45;Atorvastatin A8 intermediate 4R6S Diastereomer;Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6S)-Isomer;(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate;tert-Butyl 2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate;(4R,6S)-1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester;1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)-
CBNumber
CB62664118
Molecular Formula
C14H23NO4
Formula Weight
269.34
MOL File
196085-84-4.mol
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(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Property

Boiling point:
364.1±17.0 °C(Predicted)
Density 
1.016±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C981895
Product name
(4R,6S)-6-(Cyanomethyl)-2,2-dimethyl--1,3-dioxane-4-aceticAcidtert-ButylEster
Packaging
10mg
Price
$155
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0033545
Product name
TERT-BUTYL-2-((4R,6S)-6-(CYANOMETHYL)-2,2-DIMETHYL-1,3-DIOXAN-4-YL)ACETATE
Purity
95.00%
Packaging
5MG
Price
$503.73
Updated
2021/12/16
Alichem
Product number
196085844
Product name
tert-Butyl2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
Packaging
1g
Price
$2520
Updated
2021/12/16
Crysdot
Product number
CD11171218
Product name
tert-Butyl2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
Purity
95+%
Packaging
1g
Price
$2972
Updated
2021/12/16
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(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Chemical Properties,Usage,Production

Uses

(4R,6S)-6-(Cyanomethyl)-2,2-dimethyl--1,3-dioxane-4-acetic Acid tert-Butyl Ester is an impurity in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.

(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Suppliers

China 27 India 3 United States 3 Global 33
Beijing Comparison Pharmaceutical Technology Co., Ltd
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010-010-52878169 15801002657
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sales@bjcomparison.com
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China
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Hubei XinyuanShun Chemical Co., Ltd.
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13971561712, 13995564702, 027-50664929
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027-50664927
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hbeixys2001@163.com
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China
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ChemStrong Scientific Co.,Ltd
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0755-0755-66853366 13670046396
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0755-28363542
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sales@chem-strong.com
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China
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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0510-85629785 18013409632
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051085625359
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sales@reading-chemicals.com
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Shanghai Kewel Chemical Co., Ltd.
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021-64609169 18901607656
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021-64609160
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greensnown@163.com
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China
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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025-66113011 18112977050
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cb6@aikonchem.com
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China
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Shijiazhuang yaoBo Pharmaceutical Co., Ltd.
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15633056635
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2880679888@qq.com
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China
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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+86-400-002-6226 +86-13028896684;
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sales@rrkchem.com
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China
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Hangzhou Huarong Pharm Co., Ltd.
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571-86758373 +8613588754946
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0086-571-81131109
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sales@huarongpharm.com
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CHINA
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Guangzhou Dreampharm Biotechnology Co., Ltd.
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020-36607679 17825480238
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QQ 3008233717
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3008233717@qq.com
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China
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9919
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196085-84-4, (4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetateRelated Search:

P-HYDROXY ATORVASTATIN LACTONE di(2-Hydroxy Atorvastatin) CalciuM Salt ATV-FX1 sodiuM salt Atorvastatin 3-Oxo Atorvastatin tert-Butyl Ester Atorvastatin Impurity 15 2,3-Dehydroxy Atorvastatin Sodium Salt Atorvastatin Impurity 20 Atorvastatin IMpurity G O-Methyl Atorvastatin Calcium Salt Ortho-Hydroxy atorvastatin calcium salt Atorvastatin Impurity 46 Atorvastatin Impurity 38 Atorvastatin Impurity 31 Difluoro Atorvastatin Acetonide tert-Butyl Ester 2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide Atorvastatin Dehydro Lactone 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt

  • (4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate
  • tert-Butyl 2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
  • Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6S)-Isomer
  • Atorvastatin Impurity 61
  • Atorvastatin A8 intermediate 4R6S Diastereomer
  • Atorvastatin Impurity Z
  • (4R,6S)-1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester
  • 1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)-
  • Atorvastatin calcium impurity 45
  • 196085-84-4