ChemicalBook > CAS DataBase List > 4-PhenylpyriMidine-2-carboxylic acid

4-PhenylpyriMidine-2-carboxylic acid

Product Name
4-PhenylpyriMidine-2-carboxylic acid
CAS No.
74647-39-5
Chemical Name
4-PhenylpyriMidine-2-carboxylic acid
Synonyms
4-Phenyl-2-pyrimidinecarboxylicacid;6-phenylpyriMidine-2-carboxylic acid;4-PhenylpyriMidine-2-carboxylic acid;2-Pyrimidinecarboxylic acid, 4-phenyl-
CBNumber
CB62665397
Molecular Formula
C11H8N2O2
Formula Weight
200.19
MOL File
74647-39-5.mol
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4-PhenylpyriMidine-2-carboxylic acid Property

Melting point:
154-156 °C(Solv: benzene (71-43-2))
Boiling point:
468.2±38.0 °C(Predicted)
Density 
1.302±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
3.02±0.10(Predicted)
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P400483
Product name
4-Phenylpyrimidine-2-carboxylicAcid
Packaging
10mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
4H58-1-118
Product name
4-Phenylpyrimidine-2-carboxylic acid
Packaging
250mg
Price
$496
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0390318
Product name
4-PHENYLPYRIMIDINE-2-CARBOXYLIC ACID
Purity
95.00%
Packaging
5MG
Price
$502.6
Updated
2021/12/16
Matrix Scientific
Product number
119920
Product name
4-Phenylpyrimidine-2-carboxylic acid
Purity
95+%
Packaging
250mg
Price
$540
Updated
2021/12/16
SynQuest Laboratories
Product number
4H58-1-118
Product name
4-Phenylpyrimidine-2-carboxylic acid
Packaging
1g
Price
$1200
Updated
2021/12/16
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4-PhenylpyriMidine-2-carboxylic acid Chemical Properties,Usage,Production

Synthesis

1491142-16-5

74647-39-5

4-Substituted phenylpyrimidine-2-carboxamide (0.025 mol) was mixed with 20% sulfuric acid solution (100 mL) and the reaction was heated at 100 °C for 5-10 h. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was poured into an ice/water mixture under vigorous stirring, followed by collection of the precipitate by filtration and drying to give 4-substituted phenylpyrimidine-2-carboxylic acid as a light yellow solid.

References

[1] European Journal of Medicinal Chemistry, 2013, vol. 69, p. 77 - 89
[2] Patent: CN104072480, 2016, B. Location in patent: Paragraph 0239; 0240
[3] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 23, p. 6166 - 6173

4-PhenylpyriMidine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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74647-39-5, 4-PhenylpyriMidine-2-carboxylic acidRelated Search:


  • 4-PhenylpyriMidine-2-carboxylic acid
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  • 74647-39-5