4-PhenylpyriMidine-2-carboxylic acid
- Product Name
- 4-PhenylpyriMidine-2-carboxylic acid
- CAS No.
- 74647-39-5
- Chemical Name
- 4-PhenylpyriMidine-2-carboxylic acid
- Synonyms
- 4-Phenyl-2-pyrimidinecarboxylicacid;6-phenylpyriMidine-2-carboxylic acid;4-PhenylpyriMidine-2-carboxylic acid;2-Pyrimidinecarboxylic acid, 4-phenyl-
- CBNumber
- CB62665397
- Molecular Formula
- C11H8N2O2
- Formula Weight
- 200.19
- MOL File
- 74647-39-5.mol
4-PhenylpyriMidine-2-carboxylic acid Property
- Melting point:
- 154-156 °C(Solv: benzene (71-43-2))
- Boiling point:
- 468.2±38.0 °C(Predicted)
- Density
- 1.302±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 3.02±0.10(Predicted)
Safety
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P400483
- Product name
- 4-Phenylpyrimidine-2-carboxylicAcid
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 4H58-1-118
- Product name
- 4-Phenylpyrimidine-2-carboxylic acid
- Packaging
- 250mg
- Price
- $496
- Updated
- 2021/12/16
- Product number
- CHM0390318
- Product name
- 4-PHENYLPYRIMIDINE-2-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.6
- Updated
- 2021/12/16
- Product number
- 119920
- Product name
- 4-Phenylpyrimidine-2-carboxylic acid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $540
- Updated
- 2021/12/16
- Product number
- 4H58-1-118
- Product name
- 4-Phenylpyrimidine-2-carboxylic acid
- Packaging
- 1g
- Price
- $1200
- Updated
- 2021/12/16
4-PhenylpyriMidine-2-carboxylic acid Chemical Properties,Usage,Production
Synthesis
1491142-16-5
74647-39-5
4-Substituted phenylpyrimidine-2-carboxamide (0.025 mol) was mixed with 20% sulfuric acid solution (100 mL) and the reaction was heated at 100 °C for 5-10 h. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was poured into an ice/water mixture under vigorous stirring, followed by collection of the precipitate by filtration and drying to give 4-substituted phenylpyrimidine-2-carboxylic acid as a light yellow solid.
References
[1] European Journal of Medicinal Chemistry, 2013, vol. 69, p. 77 - 89
[2] Patent: CN104072480, 2016, B. Location in patent: Paragraph 0239; 0240
[3] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 23, p. 6166 - 6173
4-PhenylpyriMidine-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
4-PhenylpyriMidine-2-carboxylic acid Suppliers
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- Country
- India
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