BMX-IN-1

Product Name: BMX-IN-1
CAS No.: 1431525-23-3
Chemical Name: BMX-IN-1
Synonyms: henyl]-;BMX-IN-1;BMX inhibitor 1;BMX-IN-1 USP/EP/BP;BMX kinase inhibitor;BMX-IN-1 (BMX kinase inhibitor;6]naphthyridin-1(2H)-yl)phenyl)acrylamide;N-(2-methyl-5-(9-(4-(methylsulfonamido)phenyl)-2-oxobenzo[h][1;inhibit,BMX Kinase,BMX IN 1,Bruton tyrosine kinase,Btk,Inhibitor,BMXIN1;N-(2-Methyl-5-(9-(4-(MethylsulfonaMido)phenyl)-2-oxobenzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylaMide
CBNumber: CB62666602
Molecular Formula: C29H24N4O4S
Formula Weight: 524.59
MOL File: 1431525-23-3.mol

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BMX-IN-1 Property

Density: 1.397±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: insoluble in H2O; insoluble in EtOH; ≥5.25 mg/mL in DMSO
form: solid
pka: 7.77±0.10(Predicted)
color: White to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 5.05021
Product name: BMX-IN-1 - CAS 1431525-23-4 - Calbiochem
Packaging: 10mg
Price: $280
Updated: 2024/03/01

Cayman Chemical

Product number: 19165
Product name: BMX-IN-1
Purity: ≥95%
Packaging: 500μg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 19165
Product name: BMX-IN-1
Purity: ≥95%
Packaging: 1mg
Price: $61
Updated: 2024/03/01

Cayman Chemical

Product number: 19165
Product name: BMX-IN-1
Purity: ≥95%
Packaging: 5mg
Price: $214
Updated: 2024/03/01

Tocris

Product number: 5123
Product name: BMX-IN-1
Purity: ≥98%(HPLC)
Packaging: 5
Price: $160
Updated: 2021/12/16

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BMX-IN-1 Chemical Properties,Usage,Production

Description

BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX; IC₅₀ = 8 nM) that targets Cys⁴⁹⁶ in the BMX ATP binding domain. It additionally targets the related Bruton’s tyrosine kinase (BTK) with an IC₅₀ value of 10.4 nM, but is more than 47-656-fold less potent for inhibition of Blk, JAK3, EGFR, Itk, or Tec activity. BMX-IN-1 was shown to inhibit the proliferation of Tel-BMX-transformed Ba/F3 prostate cancer cells with a GI₅₀ value of 25 nM. Antiproliferative activity was also observed in RV-1, DU-145, PC-3, and VCAP prostate cancer cell lines (GI₅₀s = 2.54, 4.38, 5.37, and 2.46 μM, respectively).

target

BMX Kinase

storage

Store at -20°C

BMX-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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BMX-IN-1 Suppliers

China 60 India 1 United Kingdom 1 United States 12 Global 74

Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd

Tel: 18502726233; 18502726233
Email: 3641133981@qq.com
Country: China
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Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
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Shanghai Aladdin Bio-Chem Technology Co.,LTD

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MedChemexpress LLC

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Email: sales@medchemexpress.cn
Country: United States
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AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
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ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
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Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
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ShangHai KenEn Chemical Technology Co., Ltd.

Tel: 13120367189
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ShangHai AmK Pharmaceutical Technology Co., Ltd.

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LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
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1431525-23-3, BMX-IN-1Related Search:

6]naphthyridin-1(2H)-yl)phenyl)acrylamide

BMX KINASE INHIBITOR;N-(2-METHYL-5-(9-(4-(METHYLSULFONAMIDO)PHENYL)-2-OXOBENZO[H][1;6]NAPHTHYRIDIN-1(2H)-YL)PHENYL)ACRYLAMIDE

N-(2-methyl-5-(9-(4-(methylsulfonamido)phenyl)-2-oxobenzo[h][1

BMX kinase inhibitor

BMX-IN-1

N-(2-Methyl-5-(9-(4-(MethylsulfonaMido)phenyl)-2-oxobenzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylaMide

N-[2-Methyl-5-[9-[4-[(methylsulfonyl)amino]phenyl]-2-oxobenzo[h]-1,6-naphthyridin-1(2H)-yl]phenyl]-2-propenamide

henyl]-

BMX-IN-1 (BMX kinase inhibitor

BMX inhibitor 1

2-Propenamide, N-[2-methyl-5-[9-[4-[(methylsulfonyl)amino]phenyl]-2-oxobenzo[h]-1,6-naphthyridin-1(2H)-yl]phenyl]-

BMX-IN-1 USP/EP/BP

BMX-INQ: What is BMX-IN Q: What is the CAS Number of BMX-IN Q: What is the storage condition of BMX-IN

inhibit,BMX Kinase,BMX IN 1,Bruton tyrosine kinase,Btk,Inhibitor,BMXIN1

1431525-23-3