Cinacalcet Impurity D

Product Name: Cinacalcet Impurity D
CAS No.: 1271930-15-4
Chemical Name: Cinacalcet Impurity D
Synonyms: Cinacalcet USP RC B;CicalcetImpurityDHCl;CicalcetImpurity1HCl;Cinacalcet Impurity D;cinacalcet iMpurity 8;Cinacalcet Impurity D HCL;Cinacalcet tertiary amine;Cinacalcet USP Related Compound B;Cinacalcet Hydrochloride iMpuritX;Cinacalcet Impurity 5(Cinacalcet USP RC B)
CBNumber: CB62671079
Molecular Formula: C32H31F6N
Formula Weight: 543.59
MOL File: 1271930-15-4.mol

More

Less

Cinacalcet Impurity D Property

Boiling point:: 552.2±50.0 °C(Predicted)
Density: 1.203±0.06 g/cm3(Predicted)
pka: 8.40±0.50(Predicted)
InChIKey: BMWNEBVDXWCUKG-CRPMJUFNNA-N
SMILES: C(N([C@@H](C1=C2C(C=CC=C2)=CC=C1)C)CCCC1=CC=CC(C(F)(F)F)=C1)CCC1=CC=CC(C(F)(F)F)=C1 |&1:2,r|

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TRC

Product number: T791425
Product name: N-[(3-Trifluoromethyl)phenyl)propyl]Cinacalcet
Packaging: 50mg
Price: $1320
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 53292
Product name: N-[(3-Trifluoromethyl)phenyl)propyl]Cinacalcet
Packaging: 50mg
Price: $2200
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 53292
Product name: N-[(3-Trifluoromethyl)phenyl)propyl]Cinacalcet
Packaging: 5mg
Price: $650
Updated: 2021/12/16

More

Less

Cinacalcet Impurity D Chemical Properties,Usage,Production

Description

Cinacalcet Impurity D is a potential byproduct or impurity in the synthesis of the drug. It is essential to study the properties and potential implications of Cinacalcet Impurity D for pharmaceutical research. Cinacalcet is a drug commonly used for the treatment of hyperparathyroidism in patients with chronic kidney disease.

Uses

N-[(3-Trifluoromethyl)phenyl)propyl] Cinacalcet (Cinacalcet USP Related Compound B) is an impurity of Cinacalcet Hydrochloride (C441800). Cinacalcet is used in clinical trial in secondary hyperparathyroidism.

Preparation

Cinacalcet hydrochloride (11 g, 0.028 mol) in toluene (150 mL) was added to potassium carbonate (7.74 g, 0.056 mol) followed by 1-(3-bromopropyl)-3-(trifluoromethyl)benzene (14.95 g, 0.056 mol) under stirring at 25-30 °C. The reaction was heated and stirred at 110-111 °C for 48 h. Upon completion of the reaction (by TLC), the reaction was cooled and quenched with water (100 mL). The organic layer was separated, washed with water (100 mL), and concentrated under reduced pressure to obtain a thick oil. The crude oil was then purified by column chromatography on silica gel by eluting with chloroform to afford Cinacalcet Impurity D as a thick transparent oil.

Cinacalcet Impurity D Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Cinacalcet Impurity D Suppliers

China 44 India 3 United States 4 Global 51

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-66023220 0086-15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 7892
Advantage: 55

Tonichem Pharmaceutical Technology Co., Ltd.

Tel: +86 (0752) 222-7171, +86 15815821171
Fax: +86 (0752) 222-6171
Country: China
ProdList: 1120
Advantage: 58

Roark Standards

Tel: 0755-83552066 15986688328
Fax: 0755-83552066
Email: service@roarkstandards.com
Country: China
ProdList: 1442
Advantage: 58

Shijiazhuang yaoBo Pharmaceutical Co., Ltd.

Tel: 15633056635
Email: 2880679888@qq.com
Country: China
ProdList: 2920
Advantage: 58

Hubei Yangxin Medical Technology Co., Ltd.

Tel: 15374522761
Fax: QQ:2853117752
Email: 3003392093@qq.com
Country: China
ProdList: 8705
Advantage: 55

Shanghai CR Corporation Limited

Tel: 021-80270511; 4006653949
Fax: QQ: 2136646215
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 10044
Advantage: 58

Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-28967200 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9578
Advantage: 60

1271930-15-4, Cinacalcet Impurity DRelated Search:

N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide (αR)-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl)propyl]-1-napthaleneMethanaMine-N-oxide 1-NaphthaleneMethanaMine, 7,8-dihydro-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl]propyl]-, hydrochloride (1:1), (αR)- 1-(7,8-dihydronaphthalen-1-yl)ethan-1-amine hydrochloride Cinacalcene Impurity I Cinacalcet impurity C Cinacalcet Impurity 22 N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide Cinacalcet Impurity 21 (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoroMethyl)phenyl)propan-1-aMine Cinacalcet IMpurity 6 Cinacalcet IMpurity 3 (E)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)acrylamide Cinacalcet IMpurity 9 (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(M-tolyl)propan-1-aMine N-(1-(5,6,7,8-tetrahydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide 1-(5,6,7,8-tetrahydronaphthalen-1-yl)ethan-1-amine hydrochloride Cinacalcet Impurity H

1-NaphthaleneMethanaMine, α-Methyl-N,N-bis[3-[3-(trifluoroMethyl)phenyl]propyl]-, (αR)-

(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)propan-1-amine

N-[(3-Trifluoromethyl)phenyl)propyl] Cinacalcet

N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]-N-[3-[3-(trifluoromethyl)phenyl]propyl]propan-1-amine

Cinacalcet Impurity D HCL

Cinacalcet USP RC B

Cinacalcet Impurity 5(Cinacalcet USP RC B)

"(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)

Cinacalcet USP Related Compound B

Cinacalcet impurity 20/(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)propan-1-amine hydrochloride

[(1R)-1-(naphthalen-1-yl)ethyl]bis({3-[3-(trifluoromethyl)phenyl]propyl})amine

(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(2-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

(R)-(1-naphthalen-1-ylethyl)-N,N-bis[3-(3-trifluoromethylphenyl)propyl]amine, hydrogen chloride

Cinacalcet Hydrochloride iMpuritX

Cinacalcet Related Compund B (Cinacalcet Impurity D)

Cinacalcet Impurity DQ: What is Cinacalcet Impurity D Q: What is the CAS Number of Cinacalcet Impurity D Q: What is the storage condition of Cinacalcet Impurity D Q: What are the applications of Cinacalcet Impurity D

Cinacalcet tertiary amine

CicalcetImpurityDHCl

CicalcetImpurity1HCl

1-Naphthalenemethanamine, α-methyl-N,N-bis[3-[3-(trifluoromethyl)phenyl]propyl]-, (αR)-

Cinacalcet Impurity D

cinacalcet iMpurity 8

1271930-15-4

C32H31F6N