(+/-)-EvodiaMine
- Product Name
- (+/-)-EvodiaMine
- CAS No.
- 518-18-3
- Chemical Name
- (+/-)-EvodiaMine
- Synonyms
- (+/-)-Evodiamine;(+/-)-Evodiamine>TXDUTHBFYKGSAH-UHFFFAOYSA-N;14-Methyl-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one;14-Methyl-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one
- CBNumber
- CB62673316
- Molecular Formula
- C19H17N3O
- Formula Weight
- 303.36
- MOL File
- 518-18-3.mol
(+/-)-EvodiaMine Property
- Melting point:
- 272°C(lit.)
- Boiling point:
- 575.1±50.0 °C(Predicted)
- Density
- 1.39±0.1 g/cm3(Predicted)
- storage temp.
- 0-10°C
- solubility
- very slightly in Acetone
- form
- powder to crystal
- pka
- 17.27±0.20(Predicted)
- color
- White to Orange to Green
- λmax
- 268nm(EtOH)(lit.)
Safety
- HS Code
- 2939.80.0000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- E1012
- Product name
- (+/-)-Evodiamine
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 1g
- Price
- $137
- Updated
- 2024/03/01
- Product number
- E975133
- Product name
- (+/-)-Evodiamine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 32473
- Product name
- (±)-Evodiamine,98%(HPLC)
- Purity
- 98%(HPLC)
- Packaging
- 250MG
- Price
- $56
- Updated
- 2021/12/16
- Product number
- 32473
- Product name
- (±)-Evodiamine,98%(HPLC)
- Purity
- 98%(HPLC)
- Packaging
- 1G
- Price
- $100.8
- Updated
- 2021/12/16
- Product number
- 32473
- Product name
- (±)-Evodiamine,98%(HPLC)
- Purity
- 98%(HPLC)
- Packaging
- 5G
- Price
- $476
- Updated
- 2021/12/16
(+/-)-EvodiaMine Chemical Properties,Usage,Production
Description
Evodiamine is extracted and isolated from the fruit of Evodiarutaecarpa (Juss.) Benth., a rutaceae plant. It is converted into Isoevodiamine after being boiled with hydrochloric acid alcohol solution.
Definition
ChEBI: LSM-6483 is a member of beta-carbolines.
Pharmacokinetics
1. Antitumor activity
Evodiamine can inhibit the proliferation of various tumor cells, including cervical cancer, colon cancer, lung cancer, melanoma, T lymphocyte-like leukemia, prostate cancer Inhibition of proliferation of various tumor cells including cancer and breast cancer.
2. Anti-senile dementia effect
3. Effects on endocrine system
Evodiamine can inhibit 3β-hydroxysteroid dehydrogenase by reducing the activity of intracellular cyclic adenosine monophosphate (cAMP) related pathways (3β-HSD) and other steroid hormone production-related enzymes, reduce and affect the expression of signal transduction and RNA activation protein (StAR), and directly act on rat adrenal cortex reticulum cells to inhibit the secretion of corticosterone.
4. Weight loss and hypoglycemic effect
5.Anti-inflammatory and analgesic effect
6. Effects on the cardiovascular system
(+/-)-EvodiaMine Preparation Products And Raw materials
Raw materials
Preparation Products
(+/-)-EvodiaMine Suppliers
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