ChemicalBook > CAS DataBase List > (+/-)-EvodiaMine

(+/-)-EvodiaMine

Product Name
(+/-)-EvodiaMine
CAS No.
518-18-3
Chemical Name
(+/-)-EvodiaMine
Synonyms
(+/-)-Evodiamine;(+/-)-Evodiamine>TXDUTHBFYKGSAH-UHFFFAOYSA-N;14-Methyl-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one;14-Methyl-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one
CBNumber
CB62673316
Molecular Formula
C19H17N3O
Formula Weight
303.36
MOL File
518-18-3.mol
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(+/-)-EvodiaMine Property

Melting point:
272°C(lit.)
Boiling point:
575.1±50.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
storage temp. 
0-10°C
solubility 
very slightly in Acetone
form 
powder to crystal
pka
17.27±0.20(Predicted)
color 
White to Orange to Green
λmax
268nm(EtOH)(lit.)
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Safety

HS Code 
2939.80.0000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1012
Product name
(+/-)-Evodiamine
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$137
Updated
2024/03/01
TRC
Product number
E975133
Product name
(+/-)-Evodiamine
Packaging
10mg
Price
$45
Updated
2021/12/16
Chem-Impex
Product number
32473
Product name
(±)-Evodiamine,98%(HPLC)
Purity
98%(HPLC)
Packaging
250MG
Price
$56
Updated
2021/12/16
Chem-Impex
Product number
32473
Product name
(±)-Evodiamine,98%(HPLC)
Purity
98%(HPLC)
Packaging
1G
Price
$100.8
Updated
2021/12/16
Chem-Impex
Product number
32473
Product name
(±)-Evodiamine,98%(HPLC)
Purity
98%(HPLC)
Packaging
5G
Price
$476
Updated
2021/12/16
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(+/-)-EvodiaMine Chemical Properties,Usage,Production

Description

Evodiamine is extracted and isolated from the fruit of Evodiarutaecarpa (Juss.) Benth., a rutaceae plant. It is converted into Isoevodiamine after being boiled with hydrochloric acid alcohol solution.

Definition

ChEBI: LSM-6483 is a member of beta-carbolines.

Pharmacokinetics

1. Antitumor activity
Evodiamine can inhibit the proliferation of various tumor cells, including cervical cancer, colon cancer, lung cancer, melanoma, T lymphocyte-like leukemia, prostate cancer Inhibition of proliferation of various tumor cells including cancer and breast cancer.
2. Anti-senile dementia effect

3. Effects on endocrine system
Evodiamine can inhibit 3β-hydroxysteroid dehydrogenase by reducing the activity of intracellular cyclic adenosine monophosphate (cAMP) related pathways (3β-HSD) and other steroid hormone production-related enzymes, reduce and affect the expression of signal transduction and RNA activation protein (StAR), and directly act on rat adrenal cortex reticulum cells to inhibit the secretion of corticosterone.
4. Weight loss and hypoglycemic effect
5.Anti-inflammatory and analgesic effect

6. Effects on the cardiovascular system

(+/-)-EvodiaMine Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-EvodiaMine Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
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TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
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TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
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TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
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9ding chemical ( Shanghai) Limited
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4009209199
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86-021-52271987
Email
sales@9dingchem.com
Country
China
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Finetech Industry Limited
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027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
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China
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Shanghai Macklin Biochemical Co.,Ltd.
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15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
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16166
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Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
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Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20)
Fax
0539-6362799(To 20)
Country
China
ProdList
10007
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58

518-18-3, (+/-)-EvodiaMineRelated Search:


  • TXDUTHBFYKGSAH-UHFFFAOYSA-N
  • (+/-)-Evodiamine&gt
  • (+/-)-Evodiamine
  • 14-Methyl-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one
  • 14-Methyl-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one
  • 518-18-3