5-chloro-6-iodo-2,3-dihydro-1H-1,3-benzodiazole-2-thione
- Product Name
- 5-chloro-6-iodo-2,3-dihydro-1H-1,3-benzodiazole-2-thione
- CAS No.
- 1219741-21-5
- Chemical Name
- 5-chloro-6-iodo-2,3-dihydro-1H-1,3-benzodiazole-2-thione
- Synonyms
- 5-Chloro-6-iodo-1H-benzo[d]imidazole-2(3H)-thione;5-Chloro-6-iodo-1,3-dihydro-2H-benzimidazole-2-thione;2H-Benzimidazole-2-thione, 5-chloro-1,3-dihydro-6-iodo-;5-chloro-6-iodo-2,3-dihydro-1H-1,3-benzodiazole-2-thione
- CBNumber
- CB62681779
- Molecular Formula
- C7H4ClIN2S
- Formula Weight
- 310.54
- MOL File
- 1219741-21-5.mol
5-chloro-6-iodo-2,3-dihydro-1H-1,3-benzodiazole-2-thione Property
- Boiling point:
- 374.9±52.0 °C(Predicted)
- Density
- 2.23±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 9.14±0.30(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A265480
- Product name
- 5-Chloro-6-iodo-1H-benzo[d]imidazole-2(3H)-thione
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $30
- Updated
- 2021/12/16
- Product number
- CM129809
- Product name
- 5-chloro-6-iodo-1,3-dihydro-2H-benzo[d]imidazole-2-thione
- Purity
- 95%
- Packaging
- 1g
- Price
- $234
- Updated
- 2021/12/16
- Product number
- CD11326842
- Product name
- 5-Chloro-6-iodo-1H-benzo[d]imidazole-2(3H)-thione
- Purity
- 95+%
- Packaging
- 1g
- Price
- $248
- Updated
- 2021/12/16
- Product number
- 61-11030
- Product name
- 5-Chloro-6-iodo-1H-benzo[d]imidazole-2(3H)-thione
- Purity
- 95-98%
- Packaging
- 1g
- Price
- $675
- Updated
- 2021/12/16
- Product number
- CM129809
- Product name
- 5-chloro-6-iodo-1,3-dihydro-2H-benzo[d]imidazole-2-thione
- Purity
- 95%
- Packaging
- 5g
- Price
- $701
- Updated
- 2021/12/16
5-chloro-6-iodo-2,3-dihydro-1H-1,3-benzodiazole-2-thione Chemical Properties,Usage,Production
Synthesis
75-15-0
1219741-20-4
1219741-21-5
To a 100 mL round-bottomed flask under nitrogen protection was added 4-chloro-5-iodobenzene-1,2-diamine (2.69 g, 10.02 mmol, 1.00 equiv), ethanol (50 mL), carbon disulfide (6 g, 78.95 mmol, 8.00 equiv), and potassium hydroxide (1.68 g, 30.00 mmol, 3.00 equiv). The reaction mixture was heated to reflux for 3 hours. After completion of the reaction, the mixture was concentrated under reduced pressure. The concentrate was diluted with 100 mL of water and subsequently extracted with ethyl acetate (3 x 100 mL). The organic layers were combined, washed with 100 mL of saturated saline and then dried over anhydrous sodium sulfate. The dried organic phase was concentrated under reduced pressure to give 2.5 g of 5-chloro-6-iodo-1H-benzo[d]imidazole-2(3H)-thione as a brown solid in 80% yield.
References
[1] Patent: US2013/281392, 2013, A1. Location in patent: Paragraph 0148
[2] Patent: US2010/81643, 2010, A1. Location in patent: Page/Page column 36
[3] Patent: WO2010/47982, 2010, A1. Location in patent: Page/Page column 75
[4] Patent: WO2010/51176, 2010, A1. Location in patent: Page/Page column 81
[5] Patent: WO2011/106273, 2011, A1. Location in patent: Page/Page column 66
5-chloro-6-iodo-2,3-dihydro-1H-1,3-benzodiazole-2-thione Preparation Products And Raw materials
Raw materials
Preparation Products
5-chloro-6-iodo-2,3-dihydro-1H-1,3-benzodiazole-2-thione Suppliers
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- Country
- India
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