ChemicalBook > CAS DataBase List > 6-Fluoro-5-Methoxy-2,3-dihydro-1h-inden-1-one

6-Fluoro-5-Methoxy-2,3-dihydro-1h-inden-1-one

Product Name
6-Fluoro-5-Methoxy-2,3-dihydro-1h-inden-1-one
CAS No.
295779-82-7
Chemical Name
6-Fluoro-5-Methoxy-2,3-dihydro-1h-inden-1-one
Synonyms
6-Fluoro-5-methoxy-indan-1-one;6-fluoro-5-methoxy-2,3-dihydroinden-1-one;6-Fluoro-5-Methoxy-2,3-dihydro-1h-inden-1-one;1H-Inden-1-one, 6-fluoro-2,3-dihydro-5-methoxy-
CBNumber
CB62684831
Molecular Formula
C10H9FO2
Formula Weight
180.18
MOL File
295779-82-7.mol
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6-Fluoro-5-Methoxy-2,3-dihydro-1h-inden-1-one Property

Boiling point:
312.0±42.0 °C(Predicted)
Density 
1.257±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
F600585
Product name
6-Fluoro-5-methoxy-2,3-dihydro-1H-inden-1-one
Packaging
50mg
Price
$350
Updated
2021/12/16
AK Scientific
Product number
7241DM
Product name
6-Fluoro-5-methoxy-2,3-dihydro-1H-inden-1-one
Packaging
250mg
Price
$366
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0368107
Product name
6-FLUORO-5-METHOXY-2,3-DIHYDRO-1H-INDEN-1-ONE
Purity
95.00%
Packaging
5MG
Price
$502.72
Updated
2021/12/16
AK Scientific
Product number
7241DM
Product name
6-Fluoro-5-methoxy-2,3-dihydro-1H-inden-1-one
Packaging
1g
Price
$668
Updated
2021/12/16
Alichem
Product number
295779827
Product name
6-Fluoro-5-methoxy-2,3-dihydro-1H-inden-1-one
Packaging
1g
Price
$1029
Updated
2021/12/16
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6-Fluoro-5-Methoxy-2,3-dihydro-1h-inden-1-one Chemical Properties,Usage,Production

Synthesis

864960-96-3

75-75-2

295779-82-7

The general procedure for the synthesis of 6-fluoro-5-methoxy-2,3-dihydro-1H-inden-1-one from 3-(4-fluoro-3-methoxyphenyl)propionic acid (2 g, 10 mmol) and methanesulfonic acid (15 ml) is as follows: 3-(4-fluoro-3-methoxyphenyl)propionic acid was sealed with methanesulfonic acid in a 20 ml process vial, and the reaction was carried out by heating under microwave radiation at 90°C for for 10 minutes. After completion of the reaction, the mixture was poured into ice water and neutralized with sodium hydroxide solution. Subsequently, the precipitated solid product was collected and dried to give 1.7 g of the target compound in 93.5% yield. The result of the material spectrum analysis of the product: LC-MS m/e 181 (MH+).

References

[1] Patent: WO2007/71348, 2007, A1. Location in patent: Page/Page column 78

6-Fluoro-5-Methoxy-2,3-dihydro-1h-inden-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Fluoro-5-Methoxy-2,3-dihydro-1h-inden-1-one Suppliers

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295779-82-7, 6-Fluoro-5-Methoxy-2,3-dihydro-1h-inden-1-oneRelated Search:


  • 6-Fluoro-5-Methoxy-2,3-dihydro-1h-inden-1-one
  • 6-Fluoro-5-methoxy-indan-1-one
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  • 1H-Inden-1-one, 6-fluoro-2,3-dihydro-5-methoxy-
  • 295779-82-7