ChemicalBook > CAS DataBase List > 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester

3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester

Product Name
3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester
CAS No.
890190-22-4
Chemical Name
3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester
Synonyms
WDR5-0103;WDR50103, >98%;WDR5(WDR5-0103);WD-Repeat Protein 5-0103;WD-REPEAT PROTEIN 5-0103;WDR5 0103;WDR50103;Methyl 3-(3-methoxybenzamido)-4-(4-methylpiperazin-1-yl)benzoate;3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester;Benzoic acid, 3-[(3-methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)-, methyl ester
CBNumber
CB62695169
Molecular Formula
C21H25N3O4
Formula Weight
383.44
MOL File
890190-22-4.mol
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3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester Property

Boiling point:
495.2±45.0 °C(Predicted)
Density 
1.223±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO: soluble10mg/mL, clear
form 
powder
pka
12.96±0.70(Predicted)
color 
white to beige
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Safety

Hazard Codes 
N
Risk Statements 
50/53
Safety Statements 
60-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
13945
Product name
WDR5-0103
Purity
≥95%
Packaging
1mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
13945
Product name
WDR5-0103
Purity
≥95%
Packaging
5mg
Price
$270
Updated
2024/03/01
Cayman Chemical
Product number
13945
Product name
WDR5-0103
Purity
≥95%
Packaging
10mg
Price
$477
Updated
2024/03/01
Cayman Chemical
Product number
13945
Product name
WDR5-0103
Purity
≥95%
Packaging
25mg
Price
$1041
Updated
2024/03/01
Tocris
Product number
5323
Product name
WDR50103
Purity
≥99%(HPLC)
Packaging
50
Price
$647
Updated
2021/12/16
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3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester Chemical Properties,Usage,Production

Description

WD-repeat protein 5 (WDR5) is a scaffold protein commonly involved in the formation of nucleosome-modifying protein complexes with histones. For example, WDR5 is a component of a mixed-lineage leukemia (MLL) methyltransferase complex that targets histone 3. WDR5 can also be a component of histone acetyltransferase complexes and can directly bind methylated as well as unmodified histones. WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 (Kd = 450 nM), inhibiting the catalytic activity of the MLL core complex in vitro (IC50 = 39 μM).

Uses

3-[(3-Methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)benzoic Acid Methyl Ester is an small molecule inhibitor of WDR5, an essential componet of the human trithorax-like famliy of SET1 methyltransferase complexes that carry out trimethylation of histone 3 Lys4.

storage

Store at +4°C

3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester Suppliers

Canada 1 China 72 United Kingdom 1 United States 11 Global 85
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View Lastest Price from 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester manufacturers

Career Henan Chemical Co
Product
3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester 890190-22-4
Price
US $0.10/g
Min. Order
1g
Purity
98%min
Supply Ability
10g,100g
Release date
2020-01-09

890190-22-4, 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl EsterRelated Search:


  • 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester
  • Methyl 3-(3-methoxybenzamido)-4-(4-methylpiperazin-1-yl)benzoate
  • WDR5-0103
  • WDR50103, >98%
  • WD-Repeat Protein 5-0103
  • WD-REPEAT PROTEIN 5-0103;WDR5 0103;WDR50103
  • Benzoic acid, 3-[(3-methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)-, methyl ester
  • WDR5(WDR5-0103)
  • 890190-22-4
  • Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals