ChemicalBook > CAS DataBase List > 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester

3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester

Product Name
3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester
CAS No.
890190-22-4
Chemical Name
3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester
Synonyms
WDR5-0103;WDR50103, >98%;WDR5(WDR5-0103);WD-Repeat Protein 5-0103;WD-REPEAT PROTEIN 5-0103;WDR5 0103;WDR50103;Methyl 3-(3-methoxybenzamido)-4-(4-methylpiperazin-1-yl)benzoate;3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester;Benzoic acid, 3-[(3-methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)-, methyl ester
CBNumber
CB62695169
Molecular Formula
C21H25N3O4
Formula Weight
383.44
MOL File
890190-22-4.mol
More
Less

3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester Property

Boiling point:
495.2±45.0 °C(Predicted)
Density 
1.223±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO: soluble10mg/mL, clear
form 
powder
pka
12.96±0.70(Predicted)
color 
white to beige
More
Less

Safety

Hazard Codes 
N
Risk Statements 
50/53
Safety Statements 
60-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
13945
Product name
WDR5-0103
Purity
≥95%
Packaging
1mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
13945
Product name
WDR5-0103
Purity
≥95%
Packaging
5mg
Price
$270
Updated
2024/03/01
Cayman Chemical
Product number
13945
Product name
WDR5-0103
Purity
≥95%
Packaging
10mg
Price
$477
Updated
2024/03/01
Cayman Chemical
Product number
13945
Product name
WDR5-0103
Purity
≥95%
Packaging
25mg
Price
$1041
Updated
2024/03/01
Tocris
Product number
5323
Product name
WDR50103
Purity
≥99%(HPLC)
Packaging
50
Price
$647
Updated
2021/12/16
More
Less

3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester Chemical Properties,Usage,Production

Description

WD-repeat protein 5 (WDR5) is a scaffold protein commonly involved in the formation of nucleosome-modifying protein complexes with histones. For example, WDR5 is a component of a mixed-lineage leukemia (MLL) methyltransferase complex that targets histone 3. WDR5 can also be a component of histone acetyltransferase complexes and can directly bind methylated as well as unmodified histones. WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 (Kd = 450 nM), inhibiting the catalytic activity of the MLL core complex in vitro (IC50 = 39 μM).

Uses

3-[(3-Methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)benzoic Acid Methyl Ester is an small molecule inhibitor of WDR5, an essential componet of the human trithorax-like famliy of SET1 methyltransferase complexes that carry out trimethylation of histone 3 Lys4.

storage

Store at +4°C

3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester Suppliers

Canada 1 China 75 United Kingdom 1 United States 12 Global 89
Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77
More
Less

View Lastest Price from 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester manufacturers

Career Henan Chemical Co
Product
3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester 890190-22-4
Price
US $0.10/g
Min. Order
1g
Purity
98%min
Supply Ability
10g,100g
Release date
2020-01-09

890190-22-4, 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl EsterRelated Search:


  • 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester
  • Methyl 3-(3-methoxybenzamido)-4-(4-methylpiperazin-1-yl)benzoate
  • WDR5-0103
  • WDR50103, >98%
  • WD-Repeat Protein 5-0103
  • WD-REPEAT PROTEIN 5-0103;WDR5 0103;WDR50103
  • Benzoic acid, 3-[(3-methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)-, methyl ester
  • WDR5(WDR5-0103)
  • 890190-22-4
  • Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals