ChemicalBook > CAS DataBase List > 5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide

5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide

Product Name
5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide
CAS No.
1252927-47-1
Chemical Name
5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide
Synonyms
GSK-1071306;N-Demethyl Pazopanib;Pazopanib Impurity 13;Pazopanib Impurity 41;Pazopanib impurity 02;Pazopanib Impurity 56;Pazopanib metabolite M27;Pazopanib metabolite M27 HCl;Pazopanib N-Desmethyl Impurity;Pazopanib metabolite M27 Hydrochloride
CBNumber
CB62695422
Molecular Formula
C20H21N7O2S
Formula Weight
423.49144
MOL File
1252927-47-1.mol
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5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide Property

Melting point:
>252°C (dec.)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Ethyl Acetate (Slightly)
form 
Solid
color 
Pale Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D474025
Product name
N-DemethylPazopanib
Packaging
50mg
Price
$845
Updated
2021/12/16
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5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide Chemical Properties,Usage,Production

Uses

5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)amino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide is a Pazopanib (P210925) impurity. Pazopanib is an oral angiogenesis inhibitor targeting VEGFR and PDGFR.

Uses

N-demethyl Pazopanib is a Pazopanib (P210925) impurity. Pazopanib is an oral angiogenesis inhibitor targeting VEGFR and PDGFR.

5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide Preparation Products And Raw materials

Raw materials

Preparation Products

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5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide Suppliers

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1252927-47-1, 5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMideRelated Search:

3-(5-Methyl-3-phenylisoxazol-4-yl)benzenesulfonaMide 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE 2(1H)-Pyrimidinone, 4-chloro- (6CI,9CI) Pazopanib Pazopanib-d6 2,3-dimethyl-2H-indazol-6-amine hydrochloride 3-AMINO-4-METHYLBENZENESULFONAMIDE 4(1H)-Pyrimidinone, 2-chloro- (9CI) 1,3-DiMethyl-6-aMino-1H-indazole 3-Methyl-6-nitro-2H-indazole 1,3-Dimethyl-6-nitro-1H-indazole Pazopanib Impurity 9 N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine Pazopanib Related Compound 3 2-Methyl-5-nitrobenzenesulfonamide Pazopanib Related Compound 2 N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine

  • GSK-1071306
  • 5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide
  • Pazopanib Impurity 13
  • N-Demethyl Pazopanib
  • Pazopanib N-Desmethyl Impurity
  • Benzenesulfonamide, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)amino]-2-pyrimidinyl]amino]-2-methyl-
  • Pazopanib Impurity 41
  • 5-[[4-[(2,3-dimethylindazol-6-yl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide
  • Pazopanib metabolite M27 HCl
  • Pazopanib metabolite M27
  • Pazopanib metabolite M27 Hydrochloride
  • Pazopanib impurity 02
  • Pazopanib Impurity 56
  • 1252927-47-1
  • Metabolites & Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals