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cis-Atovaquone

Product Name
cis-Atovaquone
CAS No.
137732-39-9
Chemical Name
cis-Atovaquone
Synonyms
cis-Atovaquone;cis-Atovaquone-d4;Atovaquone EP Imp B;Atovaquone Impurity 17;Atovaquone EP Impurity B;cis-Atovaquone (Racemic);Atovaquone EP Impurity B (RC A);Atovaquone Impurity 2(Atovaquone EP Impurity B);Atovaquone EP Impurity B (Atovaquone Related Compound A);Atovaquone EP Impurity B (Atovaquone USP Related Compound A)
CBNumber
CB62695710
Molecular Formula
C22H19ClO3
Formula Weight
366.84
MOL File
137732-39-9.mol
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cis-Atovaquone Property

Melting point:
>40°C (dec.)
Boiling point:
535.0±50.0 °C(Predicted)
Density 
1.349±0.06 g/cm3(Predicted)
storage temp. 
Room Temperature, under inert atmosphere
solubility 
Chloroform (Slightly), Dichloromethane (Slightly, Acetonitrile)
pka
5.01±0.10(Predicted)
form 
Solid
color 
Pale Yellow to Light Yellow
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1044662
Product name
Atovaquone Related Compound A
Packaging
25mg
Price
$1300
Updated
2024/03/01
TRC
Product number
A793450
Product name
cis-Atovaquone
Packaging
1mg
Price
$145
Updated
2021/12/16
Usbiological
Product number
163131
Product name
cis-Atovaquone
Packaging
1mg
Price
$460
Updated
2021/12/16
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cis-Atovaquone Chemical Properties,Usage,Production

Uses

cis-Atovaquone is the cis-isomer of Atovaquone (A793500), a hydroxynaphthoquinone derivative that inhibits mitochondrial electron transport.

Definition

ChEBI: Atovaquone is a naphthoquinone compound having a 4-(4-chlorophenyl)cyclohexyl group at the 2-position and a hydroxy substituent at the 3-position. It has a role as an antimalarial, an antifungal agent, an EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor, an EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor and an EC 1.10.2.2 (quinol--cytochrome-c reductase) inhibitor. It is a member of monochlorobenzenes and a hydroxy-1,4-naphthoquinone.

cis-Atovaquone Preparation Products And Raw materials

Raw materials

Preparation Products

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cis-Atovaquone Suppliers

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137732-39-9, cis-AtovaquoneRelated Search:


  • Atovaquone EP Imp B
  • Atovaquone Impurity 2(Atovaquone EP Impurity B)
  • Atovaquone EP Impurity B (RC A)
  • cis-Atovaquone-d4
  • 1,4-Naphthalenedione,2-[cis-4-(4-chlorophenyl)cyclohexyl]-3- hydroxy-
  • Atovaquone EP Impurity B (Atovaquone Related Compound A)
  • 2-((1s,4s)-4-(4-chlorophenyl)cyclohexyl)-3- hydroxynaphthalene-1,4-dione
  • Atovaquone EP Impurity B
  • Atovaquone EP Impurity B (Atovaquone USP Related Compound A)
  • 2-[cis-4-(4-Chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione
  • Atovaquone Impurity 17
  • 2-(cis-4-(4-Chlorophenyl)cyclohexyl)-3-hydroxynaphthalene-1,4-dione (Atovaquone Impurity)
  • cis-Atovaquone (Racemic)
  • cis-Atovaquone
  • Atovaquone EP Impurity B (Atovaquone USP Related Compound A) (cis atovaquone)
  • 137732-39-9
  • Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals