Di-tert-butyl disulfide Property

Melting point:

-5 °C

Boiling point:

200-201 °C(lit.)

Density 

0.923 g/mL at 25 °C(lit.)

vapor density 

5 (vs air)

vapor pressure 

51.7 mm Hg ( 37.7 °C)

refractive index 

n20/D 1.490(lit.)

Flash point:

144 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Sparingly), Ethanol (Slightly)

form 

Liquid

color 

Clear pale yellow to yellow

explosive limit

0.8%(V)

Odor Threshold

0.0018ppm

BRN 

1698170

InChIKey

BKCNDTDWDGQHSD-UHFFFAOYSA-N

LogP

4.698 (est)

CAS DataBase Reference

110-06-5(CAS DataBase Reference)

EPA Substance Registry System

Disulfide, bis(1,1-dimethylethyl) (110-06-5)

Safety

Hazard Codes 

N

Risk Statements 

51/53-43-36/37/38

Safety Statements 

61-37/39-26-24

RIDADR 

UN 3082 9/PG 3

WGK Germany 

2

HazardClass 

6.1(b)

PackingGroup 

III

HS Code 

29309090

Toxicity

LD50 orally in Rabbit: 6200 mg/kg LD50 dermal Rabbit > 2000 mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

Di-tert-butyl disulfide Chemical Properties,Usage,Production

Description

Di-tert-butyl disulfide is one of the important organic intermediates.It is an important raw material for the synthesis of disulfide bond-containing sulfinyl and oxythio compounds. It can be used as a vulcanizing agent for rubber and elastomers in industry. It is also a monomer for the synthesis of proteins and other biologically active molecules.

Chemical Properties

clear pale yellow to yellow liquid

Uses

Di-tert-butyl disulfide is used in the preparation of gold-supported thin film from symmetrical and mixed disulphide adsorbates.
Mechanism of the oxidation of di-tert-butyl disulfide in the presence of H2O2 catalyzed by bis(acetylacetonato)oxovanadium and a chiral Schiff-base ligand has been investigated.
Di-tert-butyl disulfide has been used in the preparation of gold-supported thin film from symmetrical and mixed disulphide adsorbates.

Uses

Di-tert-Butyl Disulfide is a general reagent used in the synthesis of a novel neuropeptide Y (NPY) Y5 receptor antagonist Velneperit) used in the treatment of obesity.

Synthesis Reference(s)

Synthetic Communications, 13, p. 611, 1983 DOI: 10.1080/00397918308059536
Synthesis, p. 669, 1978 DOI: 10.1055/s-1978-24844
Tetrahedron Letters, 31, p. 3591, 1990 DOI: 10.1016/S0040-4039(00)94450-2

General Description

Mechanism of the oxidation of di-tert-butyl disulfide in the presence of H₂O₂ catalyzed by bis(acetylacetonato)oxovanadium and a chiral Schiff-base ligand has been investigated.