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UM729

Product Name
UM729
CAS No.
1448723-60-1
Chemical Name
UM729
Synonyms
C07;UM729;CS-1240;UM-729;UM 729;UM729 USP/EP/BP;methyl 4-(3-(piperidin-1-yl)propylamino)-9H-pyrimido[4,5-b]indole-7-carboxylate;4-[[3-(1-Piperidinyl)propyl]amino]-9H-pyrimido[4,5-b]indole-7-carboxylic acid methyl ester;9H-Pyrimido[4,5-b]indole-7-carboxylic acid, 4-[[3-(1-piperidinyl)propyl]amino]-, methyl ester
CBNumber
CB62715674
Molecular Formula
C20H25N5O2
Formula Weight
367.44
MOL File
1448723-60-1.mol
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb612002
Product name
UM729
Purity
>98%
Packaging
100mg
Price
$912.9
Updated
2021/12/16
Biorbyt Ltd
Product number
orb612002
Product name
UM729
Purity
>98%
Packaging
250mg
Price
$1654.1
Updated
2021/12/16
Biorbyt Ltd
Product number
orb612002
Product name
UM729
Purity
>98%
Packaging
1g
Price
$3432.3
Updated
2021/12/16
DC Chemicals
Product number
DC8141
Product name
UM729
Purity
>98%
Packaging
1g
Price
$2300
Updated
2021/12/16
DC Chemicals
Product number
DC8141
Product name
UM729
Purity
>98%
Packaging
250mg
Price
$1100
Updated
2021/12/16
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UM729 Chemical Properties,Usage,Production

Biological Activity

UM729 is an enhancer of aryl hydrocarbon receptor (AhR) antagonists.

in vitro

um729 expands normal hematopoietic stem and progenitor cells (HSPC) in an AhR-independent manner, and UM729 inhibits AML cell differentiation. In 05H163 cells, the addition of UM729 increased CD34+CD15- Number of cells. It can inhibit the differentiation of most AML cells in combination with AhR antagonists.

in vivo

In NSG mice, UM729, alone or in combination with SR1, enhanced engraftment but not leukemia stem cell (LSC) frequency distribution.

UM729 Preparation Products And Raw materials

Raw materials

Preparation Products

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UM729 Suppliers

China 41 United States 4 Global 45
Shanghai Boyle Chemical Co., Ltd.
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1448723-60-1, UM729Related Search:

SteMRegenin 1

  • UM729
  • C07
  • methyl 4-(3-(piperidin-1-yl)propylamino)-9H-pyrimido[4,5-b]indole-7-carboxylate
  • 4-[[3-(1-Piperidinyl)propyl]amino]-9H-pyrimido[4,5-b]indole-7-carboxylic acid methyl ester
  • CS-1240
  • UM-729;UM 729
  • 9H-Pyrimido[4,5-b]indole-7-carboxylic acid, 4-[[3-(1-piperidinyl)propyl]amino]-, methyl ester
  • UM729 USP/EP/BP
  • 1448723-60-1
  • Inhibitors