TAK-063

Product Name: TAK-063
CAS No.: 1238697-26-1
Chemical Name: TAK-063
Synonyms: CS-1534;TAK-063;Balipodect;TAK 063;TAK063;TAK-063(Balipodect);TAK063, TAK 063, TAK-063, BALIPODECT;1-[2-Fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one;4(1H)-Pyridazinone, 1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)-; Pyridone 6[1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one]
CBNumber: CB62735539
Molecular Formula: C23H17FN6O2
Formula Weight: 428.42
MOL File: 1238697-26-1.mol

More

Less

TAK-063 Property

Boiling point:: 612.3±65.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:55.0(Max Conc. mg/mL);128.38(Max Conc. mM)
form: A crystalline solid
pka: -0.34±0.12(Predicted)
color: Light yellow to yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 22208
Product name: TAK-063
Purity: ≥98%
Packaging: 5mg
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 22208
Product name: TAK-063
Purity: ≥98%
Packaging: 10mg
Price: $135
Updated: 2024/03/01

Cayman Chemical

Product number: 22208
Product name: TAK-063
Purity: ≥98%
Packaging: 25mg
Price: $212
Updated: 2024/03/01

Cayman Chemical

Product number: 22208
Product name: TAK-063
Purity: ≥98%
Packaging: 50mg
Price: $336
Updated: 2024/03/01

ChemScene

Product number: CS-3551
Product name: Balipodect
Purity: 98.69%
Packaging: 5mg
Price: $84
Updated: 2021/12/16

More

Less

TAK-063 Chemical Properties,Usage,Production

Description

TAK-063 is a potent inhibitor of phosphodiesterase 10A (PDE10A; IC₅₀ = 0.3 nM). It is >15,000-fold selective for PDE10A over other PDEs and exhibits <50% inhibition at 91 receptors, ion channels, and enzymes at a concentration of 10 μM. TAK-063 (0.3 mg/kg) increases cAMP and cGMP levels by 1.3- and 2.14-fold, respectively, in the striatum of mice. It reverses hyperlocomotion induced by PCP (Item Nos. 14276 | ISO60194) with a minimum effective dose (MED) of 0.3 mg/kg, p.o., in wild-type mice but has no effect in PDE10A knockout mice at doses up to 1 mg/kg. TAK-063 also reverses hyperlocomotion induced by (+)-MK-801 (MED = 0.1 mg/kg, p.o.) but has no effect on plasma prolactin or glucose levels in rats.

TAK-063 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

TAK-063 Suppliers

China 74 The Netherlands 1 United States 8 Global 83

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

Axon Medchem LLC

Tel: --
Fax: --
Email: info@axonmedchem.com
Country: United States
ProdList: 763
Advantage: 58

More

Less

View Lastest Price from TAK-063 manufacturers

Career Henan Chemical Co

Product: Pyridone 6[1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one] 1238697-26-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2019-12-30

1238697-26-1, TAK-063Related Search:

RESATORVID TAK-960 TAK-733 Vonoprazan fumarate INK1117

TAK-063

1-[2-Fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one

Balipodect

TAK 063;TAK063

Pyridone 6[1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one]

CS-1534

TAK-063(Balipodect)

TAK063, TAK 063, TAK-063, BALIPODECT

4(1H)-Pyridazinone, 1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)-

1238697-26-1

C23H17FN6O2

Inhibitors