TAK-063

Product Name: TAK-063
CAS No.: 1238697-26-1
Chemical Name: TAK-063
Synonyms: CS-1534;TAK-063;Balipodect;TAK 063;TAK063;TAK-063(Balipodect);TAK063, TAK 063, TAK-063, BALIPODECT;1-[2-Fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one;4(1H)-Pyridazinone, 1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)-; Pyridone 6[1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one]
CBNumber: CB62735539
Molecular Formula: C23H17FN6O2
Formula Weight: 428.42
MOL File: 1238697-26-1.mol

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TAK-063 Property

Boiling point:: 612.3±65.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:55.0(Max Conc. mg/mL);128.38(Max Conc. mM)
form: A crystalline solid
pka: -0.34±0.12(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22208
Product name: TAK-063
Purity: ≥98%
Packaging: 5mg
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 22208
Product name: TAK-063
Purity: ≥98%
Packaging: 10mg
Price: $135
Updated: 2024/03/01

Cayman Chemical

Product number: 22208
Product name: TAK-063
Purity: ≥98%
Packaging: 25mg
Price: $212
Updated: 2024/03/01

Cayman Chemical

Product number: 22208
Product name: TAK-063
Purity: ≥98%
Packaging: 50mg
Price: $336
Updated: 2024/03/01

ChemScene

Product number: CS-3551
Product name: Balipodect
Purity: 98.69%
Packaging: 5mg
Price: $84
Updated: 2021/12/16

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TAK-063 Chemical Properties,Usage,Production

Description

TAK-063 is a potent inhibitor of phosphodiesterase 10A (PDE10A; IC₅₀ = 0.3 nM). It is >15,000-fold selective for PDE10A over other PDEs and exhibits <50% inhibition at 91 receptors, ion channels, and enzymes at a concentration of 10 μM. TAK-063 (0.3 mg/kg) increases cAMP and cGMP levels by 1.3- and 2.14-fold, respectively, in the striatum of mice. It reverses hyperlocomotion induced by PCP (Item Nos. 14276 | ISO60194) with a minimum effective dose (MED) of 0.3 mg/kg, p.o., in wild-type mice but has no effect in PDE10A knockout mice at doses up to 1 mg/kg. TAK-063 also reverses hyperlocomotion induced by (+)-MK-801 (MED = 0.1 mg/kg, p.o.) but has no effect on plasma prolactin or glucose levels in rats.

TAK-063 Preparation Products And Raw materials

Raw materials

Preparation Products

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TAK-063 Suppliers

China 74 The Netherlands 1 United States 8 Global 83

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4662
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

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View Lastest Price from TAK-063 manufacturers

Career Henan Chemical Co

Product: Pyridone 6[1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one] 1238697-26-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2019-12-30

1238697-26-1, TAK-063Related Search:

RESATORVID TAK-960 TAK-733 Vonoprazan fumarate INK1117

TAK-063

1-[2-Fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one

Balipodect

TAK 063;TAK063

Pyridone 6[1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one]

CS-1534

TAK-063(Balipodect)

TAK063, TAK 063, TAK-063, BALIPODECT

4(1H)-Pyridazinone, 1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)-

1238697-26-1

C23H17FN6O2

Inhibitors