6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride
- Product Name
- 6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride
- CAS No.
- 789488-77-3
- Chemical Name
- 6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride
- Synonyms
- ENMD-1068;ENMD-1068 HCl;ENMD-1068 (ENMD1068);ENMD-1068 hydrochloride;ENMD1068 HCl,ENMD 1068 HCl;6-amino-1-[4-(3-methylbutanoyl)piperazin-1-yl]hexan-1-one;1-Hexanone, 6-amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-;ENMD-1068 HCl|||ENMD 1068|||ENMD-1068|||ENMD1068|||ENMD-1068 hydrochloride;6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride
- CBNumber
- CB62750611
- Molecular Formula
- C15H29N3O2
- Formula Weight
- 283.41
- MOL File
- 789488-77-3.mol
6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride Property
- Boiling point:
- 478.7±40.0 °C(Predicted)
- Density
- 1.047±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- H2O: soluble25mg/mL, clear
- form
- powder
- pka
- 10.57±0.10(Predicted)
- color
- white to beige
- Water Solubility
- Water: 25 mg/mL,clear
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SML1039
- Product name
- ENMD-1068 hydrochloride
- Purity
- ≥97% (HPLC)
- Packaging
- 5mg
- Price
- $120
- Updated
- 2024/03/01
- Product number
- SML1039
- Product name
- ENMD-1068 hydrochloride
- Purity
- ≥97% (HPLC)
- Packaging
- 25mg
- Price
- $476
- Updated
- 2024/03/01
- Product number
- CS-0090095
- Product name
- ENMD-1068 hydrochloride
- Purity
- 98.18%
- Packaging
- 50mg
- Price
- $600
- Updated
- 2021/12/16
- Product number
- 3785BB
- Product name
- 6-Amino-1-[4-(3-methylbutanoyl)piperazin-1-yl]hexan-1-one
- Packaging
- 500mg
- Price
- $628
- Updated
- 2021/12/16
- Product number
- CHM0121711
- Product name
- 6-AMINO-1-[4-(3-METHYLBUTANOYL)PIPERAZIN-1-YL]HEXAN-1-ONE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $925.31
- Updated
- 2021/12/16
6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride Chemical Properties,Usage,Production
Uses
ENMD-1068 hydrochloride has been used as a protease-activated receptor 2 (PAR2) antagonist to determine the pathway responsible for paw edema induced by Crotalus durissus terrificus venom serine protease (Cdtsp 2).
Biochem/physiol Actions
ENMD-1068 is an antagonist of protease-activated receptor 2 (PAR2). The compound blocks TNFα production in synovial explants from patients with arthritis, and inhibits mast cell tryptase-induced recruitment of eosinophils into the pleural cavity of mice.
6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride Suppliers
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