LGD-2226

Product Name: LGD-2226
CAS No.: 328947-93-9
Chemical Name: LGD-2226
Synonyms: LGD-2226;LGD-2226 (LGD2226);6-[Bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-2(1H)-quinolinone;6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1H-quinolin-2-one;2(1H)-Quinolinone, 6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-
CBNumber: CB62750752
Molecular Formula: C14H9F9N2O
Formula Weight: 392.22
MOL File: 328947-93-9.mol

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LGD-2226 Property

Melting point:: 187-190°C
Boiling point:: 364.4±42.0 °C(Predicted)
Density: 1.526±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 9.88±0.70(Predicted)
color: Pale Yellow to Light Yellow
BRN: 10716241
InChI: InChI=1S/C14H9F9N2O/c15-12(16,17)5-25(6-13(18,19)20)7-1-2-10-8(3-7)9(14(21,22)23)4-11(26)24-10/h1-4H,5-6H2,(H,24,26)
InChIKey: ULBPQWIGZUGPHU-UHFFFAOYSA-N
SMILES: N1C2=C(C=C(N(CC(F)(F)F)CC(F)(F)F)C=C2)C(C(F)(F)F)=CC1=O

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Safety

Hazard Codes: Xn
Risk Statements: 48/22
WGK Germany: 3
RTECS: VC8275240

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P314Get medical advice/attention if you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 07682
Product name: 6-[Bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-2(1H)-quinolinone
Purity: analytical standard
Packaging: 25mg
Price: $744
Updated: 2024/03/01

TRC

Product number: L397615
Product name: LGD-2226
Packaging: 5mg
Price: $110
Updated: 2021/12/16

TRC

Product number: L397615
Product name: LGD-2226
Packaging: 10mg
Price: $180
Updated: 2021/12/16

TRC

Product number: L397615
Product name: LGD-2226
Packaging: 100mg
Price: $1390
Updated: 2021/12/16

DC Chemicals

Product number: DC22137
Product name: LGD2226
Purity: >98%
Packaging: 1g
Price: $1600
Updated: 2021/12/16

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LGD-2226 Chemical Properties,Usage,Production

Uses

LGD-2226 is an orally active potent and selective androgen receptor modulator used in the treatment of muscle wasting and osteoporosis. Show to have an anabolic effect on muscle and bone tissue.

Synthesis

A 2 L round flask, under argon, was charged with a solution of the 14.00 g amine( 6-Amino-4-trifluoromethylquinolin-2(1H)-one )in 350 ml trifluoroacetic acid. 5.80 g NaBH4 was added within 1 h. The mixture was stirred at room temperature for 16 h. After that 4.50 g NaBH4 was added and then heated to 70°C for 5 h. The heating bath was removed and it was stirred at room temperature over 2 d. In several portions water was carefully added. In total 1500 ml water was slowly added. The yellow-greenish precipitate was filtered and rinsed with water. After drying, the crude product was purified by column chromatography on silica gel by using hexane-ethyl acetate (1:4), followed by a recrystallization in chloroform. 18.1 g of LGD-2226 was obtained as a bright yellow solid (76%).

LGD-2226 Preparation Products And Raw materials

Raw materials

Preparation Products

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LGD-2226 Suppliers

China 36 United States 4 Global 40

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

Wuhan wingroup Pharmaceutical Co., Ltd

Tel: +86-13296627870; +8613296627870
Fax: 0086-27-87819568
Email: info@whwingroup.com
Country: China
ProdList: 695
Advantage: 58

Hubei Ipure Biology Co., Ltd

Tel: +8613367258412
Fax: 18062427325
Email: ada@ipurechemical.com
Country: China
ProdList: 10319
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
Advantage: 58

Xi'an Lyna Bio-Tech Co., Ltd.

Tel: 029-84161958 18629577295
Fax: 029-84161958
Email: magic@lynabio.com
Country: China
ProdList: 1062
Advantage: 55

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

Tel: +86-021-61551413 +8618813727289
Email: contact@trustwe.com
Country: China
ProdList: 5738
Advantage: 58

Yichang Chanod Biomedical Technology Co,LTD

Tel: 0717-6855399 15377615856
Email: sales@sndswyy.cn
Country: China
ProdList: 79
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

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View Lastest Price from LGD-2226 manufacturers

Dorne Chemical Technology co. LTD

Product: LGD-2226 328947-93-9
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 100kg
Release date: 2024-03-26

hebei hongtan Biotechnology Co., Ltd

Product: LGD-2226 328947-93-9
Price: US $50.00-500.00/G
Min. Order: 10G
Purity: 98%
Supply Ability: 2000KG
Release date: 2024-06-06

Wuhan Senwayer Century Chemical Co.,Ltd

Product: LGD-2226 328947-93-9
Price: US $0.00/gram
Min. Order: 1gram
Purity: 99% HPLC
Supply Ability: 20 tons
Release date: 2022-12-08

328947-93-9, LGD-2226Related Search:

6-[Bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-2(1H)-quinolinone

LGD-2226

LGD-2226 (LGD2226)

2(1H)-Quinolinone, 6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-

6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1H-quinolin-2-one

328947-93-9