LGD-2226
- Product Name
- LGD-2226
- CAS No.
- 328947-93-9
- Chemical Name
- LGD-2226
- Synonyms
- LGD-2226;LGD-2226 (LGD2226);6-[Bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-2(1H)-quinolinone;6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1H-quinolin-2-one;2(1H)-Quinolinone, 6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-
- CBNumber
- CB62750752
- Molecular Formula
- C14H9F9N2O
- Formula Weight
- 392.22
- MOL File
- 328947-93-9.mol
LGD-2226 Property
- Melting point:
- 187-190°C
- Boiling point:
- 364.4±42.0 °C(Predicted)
- Density
- 1.526±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 9.88±0.70(Predicted)
- color
- Pale Yellow to Light Yellow
- BRN
- 10716241
- InChI
- InChI=1S/C14H9F9N2O/c15-12(16,17)5-25(6-13(18,19)20)7-1-2-10-8(3-7)9(14(21,22)23)4-11(26)24-10/h1-4H,5-6H2,(H,24,26)
- InChIKey
- ULBPQWIGZUGPHU-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=C(N(CC(F)(F)F)CC(F)(F)F)C=C2)C(C(F)(F)F)=CC1=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P314Get medical advice/attention if you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 07682
- Product name
- 6-[Bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-2(1H)-quinolinone
- Purity
- analytical standard
- Packaging
- 25mg
- Price
- $744
- Updated
- 2024/03/01
- Product number
- L397615
- Product name
- LGD-2226
- Packaging
- 5mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- L397615
- Product name
- LGD-2226
- Packaging
- 10mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- L397615
- Product name
- LGD-2226
- Packaging
- 100mg
- Price
- $1390
- Updated
- 2021/12/16
- Product number
- DC22137
- Product name
- LGD2226
- Purity
- >98%
- Packaging
- 100mg
- Price
- $500
- Updated
- 2021/12/16
LGD-2226 Chemical Properties,Usage,Production
Uses
LGD-2226 is an orally active potent and selective androgen receptor modulator used in the treatment of muscle wasting and osteoporosis. Show to have an anabolic effect on muscle and bone tissue.
Synthesis
A 2 L round flask, under argon, was charged with a solution of the 14.00 g amine( 6-Amino-4-trifluoromethylquinolin-2(1H)-one )in 350 ml trifluoroacetic acid. 5.80 g NaBH4 was added within 1 h. The mixture was stirred at room temperature for 16 h. After that 4.50 g NaBH4 was added and then heated to 70°C for 5 h. The heating bath was removed and it was stirred at room temperature over 2 d. In several portions water was carefully added. In total 1500 ml water was slowly added. The yellow-greenish precipitate was filtered and rinsed with water. After drying, the crude product was purified by column chromatography on silica gel by using hexane-ethyl acetate (1:4), followed by a recrystallization in chloroform. 18.1 g of LGD-2226 was obtained as a bright yellow solid (76%).
LGD-2226 Preparation Products And Raw materials
Raw materials
Preparation Products
LGD-2226 Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32161
- Advantage
- 58
- Tel
- +8613564774135
- zijue.cai@tsbiochem.com
- Country
- United States
- ProdList
- 19884
- Advantage
- 58
- Tel
- --
- Fax
- --
- chemicals@usbio.net
- Country
- United States
- ProdList
- 6214
- Advantage
- 80
- Tel
- --
- Fax
- --
- Country
- United States
- ProdList
- 6773
- Advantage
- 87
View Lastest Price from LGD-2226 manufacturers
- Product
- LGD-2226 328947-93-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2024-03-26
- Product
- LGD-2226 328947-93-9
- Price
- US $50.00-500.00/G
- Min. Order
- 10G
- Purity
- 98%
- Supply Ability
- 2000KG
- Release date
- 2024-06-06
- Product
- LGD-2226 328947-93-9
- Price
- US $0.00/gram
- Min. Order
- 1gram
- Purity
- 99% HPLC
- Supply Ability
- 20 tons
- Release date
- 2022-12-08