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1-Phenyl-1-cyclohexanecarbonitrile

Product Name
1-Phenyl-1-cyclohexanecarbonitrile
CAS No.
2201-23-2
Chemical Name
1-Phenyl-1-cyclohexanecarbonitrile
Synonyms
AKOS BBS-00005316;1-Phenylcyclohexan-carbonitrile;1-phenylcyclohexanecarbonitrile;1-PHENYL-1-CYCLOHEXANECARBONITRILE;Cyclohexanecarbonitrile, 1-phenyl-;1-Phenylcyclohexane-1-carbonitrile;1-Phenylcyclohexanecarbonitrile >1-Phenyl-1-cyclohexanecarbonitrile,97%;1-PHENYL-1-CYCLOHEXANECARBONITRILE 97%
CBNumber
CB6276104
Molecular Formula
C13H15N
Formula Weight
185.26
MOL File
2201-23-2.mol
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1-Phenyl-1-cyclohexanecarbonitrile Property

Boiling point:
141°C/7mmHg(lit.)
Density 
1.01
refractive index 
1.5332-1.5352
Flash point:
121°
storage temp. 
Sealed in dry,Room Temperature
form 
clear liquid
color 
Colorless to Light yellow to Light orange
InChI
InChI=1S/C13H15N/c14-11-13(9-5-2-6-10-13)12-7-3-1-4-8-12/h1,3-4,7-8H,2,5-6,9-10H2
InChIKey
AUXIEQKHXAYAHG-UHFFFAOYSA-N
SMILES
C1(C2=CC=CC=C2)(C#N)CCCCC1
NIST Chemistry Reference
1-Phenyl-1-cyclohexanecarbonitrile(2201-23-2)
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
36/37/39-26
RIDADR 
UN 3276 6.1/PG III
HazardClass 
6.1
PackingGroup 
III
HS Code 
29269095
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
P2253
Product name
1-Phenylcyclohexanecarbonitrile
Purity
>97.0%(GC)
Packaging
5g
Price
$99
Updated
2025/07/31
TCI Chemical
Product number
P2253
Product name
1-Phenylcyclohexanecarbonitrile
Purity
>97.0%(GC)
Packaging
25g
Price
$296
Updated
2022/04/27
TRC
Product number
P336633
Product name
1-Phenyl-1-cyclohexanecarbonitrile
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
P336633
Product name
1-Phenyl-1-cyclohexanecarbonitrile
Packaging
100mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
1140AB
Product name
1-Phenylcyclohexanecarbonitrile
Packaging
25g
Price
$477
Updated
2021/12/16
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1-Phenyl-1-cyclohexanecarbonitrile Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS TO PALE BROWN LIQUID

Synthesis

111-24-0

140-29-4

2201-23-2

GENERAL STEPS: A mixture of benzeneacetonitrile (50.0 g, 426.8 mmol) and 1,5-dibromopentane (58.1 mL, 426.8 mmol) was added slowly and dropwise to a dimethylsulfoxide (600.0 mL) suspension of NaH (42.7 g, 1067.0 mmol, 60%) at 0 °C. The mixture was pre-dissolved in a solvent mixture of dimethyl sulfoxide and ether (1:1, 200.0 mL). After dropwise addition, the reaction mixture was continued to be stirred at 0°C for 2 hours. Upon completion of the reaction, water and 10% HCl solution were added to the mixture, followed by extraction with ethyl acetate. The organic layers were combined, washed sequentially with water and brine and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give the crude product. The crude product was purified by conventional silica gel column chromatography (eluent: hexane) to afford 1-phenyl-1-cyclohexanecarbonitrile (52.0 g, yield 65.76%) as a colorless oil.GC-MS analysis showed that the molecular ion peak m/z was 185.0.

References

[1] Patent: US2014/194431, 2014, A1. Location in patent: Paragraph 0940-0942
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 14, p. 3913 - 3924
[3] Journal of Organic Chemistry, 1971, vol. 36, p. 1308 - 1309
[4] Chemische Berichte, 1973, vol. 106, p. 2890 - 2903
[5] Bulletin de la Societe Chimique de France, 1965, p. 2030 - 2037

1-Phenyl-1-cyclohexanecarbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Phenyl-1-cyclohexanecarbonitrile Suppliers

Creasyn Finechem(Tianjin) Co., Ltd.
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J & K SCIENTIFIC LTD.
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
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China
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Nanjing Habo Medical Technology Co., Ltd.
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Fax
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Maya High Purity Chemicals
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TOKYO CHEMICAL INDUSTRY CO., LTD.
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Japan
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