ChemicalBook > CAS DataBase List > Ceftezole

Ceftezole

Product Name
Ceftezole
CAS No.
26973-24-0
Chemical Name
Ceftezole
Synonyms
CTZ;CG-B 3Q;FR 10123;Celoslin;ceftezol;CEFTEZOLE;CEPHTEZOL;Ceftazole;NSC 102805;Ceftezole Acid
CBNumber
CB6277787
Molecular Formula
C13H12N8O4S3
Formula Weight
440.48
MOL File
26973-24-0.mol
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Ceftezole Property

Melting point:
155°C (dec.)
Density 
2.09
storage temp. 
Store at -20°C
solubility 
DMSO: 88 mg/mL (199.78 mM);;
pka
2.60±0.50(Predicted)
λmax
273nm(Phosphate buffer sol.)(lit.)
Merck 
14,1948
CAS DataBase Reference
26973-24-0(CAS DataBase Reference)
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Safety

Hazard Codes 
T+,N
Risk Statements 
21/22-26-50/53
Safety Statements 
28-36/37-45-61
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
716707
Product name
Cadmium zinc telluride
Purity
99.9999% trace metals basis
Packaging
5g
Price
$146
Updated
2023/01/07
TRC
Product number
C244315
Product name
Ceftezole
Packaging
10g
Price
$85
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC41103
Product name
Ceftezole
Packaging
5G
Price
$90
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC41103
Product name
Ceftezole
Packaging
10g
Price
$144
Updated
2021/12/16
AK Scientific
Product number
J11705
Product name
Ceftezole
Packaging
25mg
Price
$38
Updated
2021/12/16
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Ceftezole Chemical Properties,Usage,Production

Originator

Ceftezole,Arocor Holdings Inc.

Uses

Ceftezole is a β-lactam, cephem antibiotic. It also exhibits potent α-glucosidase inhibitory activity and antidiabetic effect in streptozotocin-induced mouse.

Uses

A direct bandgap semiconductor, it is used in a variety of applications, including radiation detectors, photorefractive gratings, electro-optic modulators, solar cells, and terahertz generation and detection. The band gap varies from approximately 1.4 to 2.2 eV, depending on composition.

Definition

ChEBI: Ceftezole is a first-generation cephalosporin antibiotic having (1,3,4-thiadiazol-2-ylsulfanyl)methyl and [2-(1H-tetrazol-1-yl)acetamido side groups located at positions 3 and 7 respectively. It is a cephalosporin and a member of thiadiazoles.

Manufacturing Process

To a solution of 1 equivalent (eq.) of 1H-tetrazole-1-acetic acid and 1 eq. of triethylamine in 20 ml of tetrahydrofuran cooled to -20°C was added 1 eq. of pivaloyl chloride. After thirty-minute stirring of the mixture 20 ml of a chloroform solution containing 1 eq. of and 1 eq. of triethylamine was poured into the solution cooled at -10°C during a period of 30 minutes. The resulting mixed solution was stirred for 30 minutes at the same temperature, for 1 hour in an ice-water mixture and for 3 hours at room temperature. Removal of a solvent from the reaction mixture afforded an oily residue, which was dissolved into 15 ml of 10% sodium bicarbonate aqueous solution. The resulting aqueous layer was adjusted to pH 1.0-2.0 with 10% hydrochloric acid, washed with ether and extracted with ethyl acetate. The extract was washed with water, dried over sodium sulfate and concentrated under reduced pressure leaving a residue which was triturated with ethyl acetate to obtain 3- acetoxymethyl-8-oxo-7-(2-tetrazol-1-acetylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid.
A solution of 1 eq. of sodium salt of 3-acetoxymethyl-8-oxo-7-(2-tetrazol-1- acetylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (it may be prepared with equivalent of sodium bicarbonate and above named acid) and 1 eq. of [1.3.4]-thiadiazole-2-thiol in 20 ml of phosphate buffer (pH 6.4) was stirred for 5.5 hours at 60°C. The reaction mixture was adjusted to pH 2.0 with 5% hydrochloric acid and treated with ethyl acetate to form a title compound - ceftezole.

Therapeutic Function

Antibiotic

General Description

Cadmium zinc telluride (Cd1-xZnxTe or CZT) can detect nuclear radiation hence, CZT with Zn concentrations between 0.1-0.2 may be used in the making of radiation detectors of X-ray and gamma-ray spectrometers.

Ceftezole Preparation Products And Raw materials

Raw materials

Preparation Products

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Ceftezole Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8850
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52
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
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65
AILY INTL CHEMICAL CORP LTD
Tel
025-83208295 18913388297
Fax
+86-2583208202
Country
China
ProdList
132
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50
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
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Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9901
Advantage
58
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23680
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TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23662
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9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
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55
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View Lastest Price from Ceftezole manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Ceftezole 26973-24-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
Ceftezole 26973-24-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Dideu Industries Group Limited
Product
Ceftezole 26973-24-0
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-29

26973-24-0, CeftezoleRelated Search:


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