Proflavine hemisulfate
- Product Name
- Proflavine hemisulfate
- CAS No.
- 1811-28-5
- Chemical Name
- Proflavine hemisulfate
- Synonyms
- PROFLAVINE HEMISULPHATE;PROFLAVINE HEMISULFATE SALT;3,6-DIAMINOACRIDINIUM MONOHYDROGEN SULFATE;PROFLAVINE SULFATE;PROFLAVINE HEMISULFATE;Proflavin hemisulphate;PROFLAVINE HEMISULFATE;bis(acridine-3,6-diamine);3,6-DIAMINOACRIDINE SULFATE;2 8-DIAMINOACRIDINE SULFATE
- CBNumber
- CB6285832
- Molecular Formula
- C13H13N3O4S
- Formula Weight
- 307.32
- MOL File
- 1811-28-5.mol
Proflavine hemisulfate Property
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO (Slightly, Heated), Water (Slightly, Heated)
- form
- powder
- color
- Orange to Amber to Dark red
- PH
- pH (1g/l, 25℃) : 4.0～8.0
- Water Solubility
- H2O: 10mg/mL
- BRN
- 3921806
- Stability:
- Hygroscopic
- EPA Substance Registry System
- 3,6-Acridinediamine, sulfate (2:1) (1811-28-5)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P2508
- Product name
- Proflavine hemisulfate salt hydrate
- Purity
- powder
- Packaging
- 10g
- Price
- $71.91
- Updated
- 2025/07/31
- Product number
- P2508
- Product name
- Proflavine hemisulfate salt hydrate
- Purity
- powder
- Packaging
- 1g
- Price
- $18.8
- Updated
- 2023/06/20
- Product number
- D0073
- Product name
- Proflavine Hemisulfate Hydrate
- Purity
- >97.0%(N)
- Packaging
- 5g
- Price
- $43
- Updated
- 2025/07/31
- Product number
- D0073
- Product name
- Proflavine Hemisulfate Hydrate
- Purity
- >97.0%(N)
- Packaging
- 25g
- Price
- $117
- Updated
- 2025/07/31
- Product number
- P2508
- Product name
- Proflavine hemisulfate salt hydrate
- Purity
- powder
- Packaging
- 25g
- Price
- $165
- Updated
- 2025/07/31
Proflavine hemisulfate Chemical Properties,Usage,Production
Description
Proflavine Hemisulfate, the hemisulfate form of proflavin, is an acridine-derived fluorescent contrast agent and disinfectant used for cell imaging and antiseptic purposes. Following topical application, proflavin diffuses into cells and intercalates into DNA, leading to its accumulation in and staining of the nucleus. This allows visualization of the nucleus during fluorescence imaging. Such capability enables nuclear morphometry and facilitates the identification of cancer cells. Additionally, proflavin sulfate exerts antimicrobial effects through binding to bacterial DNA, which disrupts DNA synthesis and inhibits bacterial cell growth.
Chemical Properties
orange to brown crystalline powder
Uses
An Acridine derivative with limited antifungal activity
Uses
Proflavine Hemisulfate is used in preparation of Adenine and Adenine nucleotides via photochemical demethylation of methyladenines.
in vivo
The concentrations of Proflavine (20 mg/kg) in whole blood after intravenous injection decreased rapidly at the beginning and remained stable from around 30 min after dosing[3].
| Animal Model: | Adult male Sprague Dawley rats (weighing approximately 200 g)[3] |
| Dosage: | 20 mg/kg (Pharmacokinetic Analysis) |
| Administration: | Intravenous injection; 2, 4, 5, 10, 15, 20, 25, and 30 min after dosing |
| Result: | Concentration decreased rapidly from whole blood in the first 5 min after dosing, followed by a slower decrease. |
Purification Methods
An aqueous solution, after treatment with charcoal, is concentrated, chilled overnight, filtered and the precipitate is rinsed with a little diethyl ether. The precipitate is dried in air, then overnight in a vacuum oven at 70o. [Beilstein 22 I 650, 22/11 V 323.]
Proflavine hemisulfate Preparation Products And Raw materials
Raw materials
Preparation Products
Proflavine hemisulfate Suppliers
- Tel
- --
- Fax
- --
- contact@ambinter.com
- Country
- France
- ProdList
- 1648
- Advantage
- 60
View Lastest Price from Proflavine hemisulfate manufacturers
- Product
- Acridine-3,6-diamine hemisulfate 1811-28-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-09-18
- Product
- Proflavine hemisulfate 1811-28-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-09-18