ChemicalBook > CAS DataBase List > (4-BROMO-2-FORMYLPHENOXY)ACETIC ACID

(4-BROMO-2-FORMYLPHENOXY)ACETIC ACID

Product Name
(4-BROMO-2-FORMYLPHENOXY)ACETIC ACID
CAS No.
24589-89-7
Chemical Name
(4-BROMO-2-FORMYLPHENOXY)ACETIC ACID
Synonyms
AKOS B005879;(4-BROMO-2-FORMYLPHENOXY)ACETIC ACID;2-(4-bromo-2-formylphenoxy)acetic acid;Acetic acid, 2-(4-bromo-2-formylphenoxy)-;2-(4-bromo-2-methanoyl-phenoxy)ethanoic acid;3-Pyridinecarboxylicacid,2,7-dimethyl-,methylester
CBNumber
CB6291291
Molecular Formula
C9H7BrO4
Formula Weight
259.05
MOL File
24589-89-7.mol
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(4-BROMO-2-FORMYLPHENOXY)ACETIC ACID Property

Boiling point:
413.6±30.0 °C(Predicted)
Density 
1.699±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
2.96±0.10(Predicted)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
8265AD
Product name
2-(4-Bromo-2-formylphenoxy)aceticacid
Packaging
250mg
Price
$126
Updated
2021/12/16
Matrix Scientific
Product number
038969
Product name
2-(4-Bromo-2-formylphenoxy)acetic acid
Packaging
500mg
Price
$126
Updated
2021/12/16
AK Scientific
Product number
8265AD
Product name
2-(4-Bromo-2-formylphenoxy)aceticacid
Packaging
1g
Price
$239
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0042550
Product name
2-(4-BROMO-2-FORMYLPHENOXY)ACETIC ACID
Purity
95.00%
Packaging
1G
Price
$771.89
Updated
2021/12/16
Abosyn
Product number
61-0553
Product name
2-(4-bromo-2-formylphenoxy)aceticacid
Purity
95-98%
Packaging
0.25g
Price
$1350
Updated
2021/12/16
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(4-BROMO-2-FORMYLPHENOXY)ACETIC ACID Chemical Properties,Usage,Production

Synthesis

51336-47-1

24589-89-7

Ethyl (4-bromo-2-formylphenoxy)acetate (60 g, 0.209 mol) was added to a mixture of LiOH (7.5 g, 0.31 mol), THF (250 mL) and water (100 mL) and stirred for 24 h at room temperature. Upon completion of the reaction, the reaction mixture was concentrated under reduced pressure and the residue was acidified to pH=2 with 1.5 N HCl. The resulting solid precipitate was filtered and dried to afford (4-bromo-2-formylphenoxy)acetic acid (50 g, 94% yield).

References

[1] Patent: WO2004/7491, 2004, A1. Location in patent: Page 51
[2] Organic Letters, 2015, vol. 17, # 23, p. 5824 - 5827
[3] European Journal of Medicinal Chemistry, 1999, vol. 34, # 12, p. 1061 - 1070

(4-BROMO-2-FORMYLPHENOXY)ACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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