ChemicalBook > CAS DataBase List > 1-BROMO-3-ETHYNYL-BENZENE

1-BROMO-3-ETHYNYL-BENZENE

Product Name
1-BROMO-3-ETHYNYL-BENZENE
CAS No.
766-81-4
Chemical Name
1-BROMO-3-ETHYNYL-BENZENE
Synonyms
3-BROMOPHENYLACETYLENE;3'-BROMOPHENYL ACETYLENE;1-BROMO-3-ETHYNYL-BENZENE;Benzene, 1-broMo-3-ethynyl-;3-Bromophenylacetylene - [B47527]
CBNumber
CB6297455
Molecular Formula
C8H5Br
Formula Weight
181.03
MOL File
766-81-4.mol
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1-BROMO-3-ETHYNYL-BENZENE Property

Boiling point:
198.24°C (rough estimate)
Density 
1.4466
refractive index 
1.5896
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
Appearance
Colorless to light yellow Liquid
InChI
InChI=1S/C8H5Br/c1-2-7-4-3-5-8(9)6-7/h1,3-6H
InChIKey
TZDXNFAAJNEYIO-UHFFFAOYSA-N
SMILES
C1(Br)=CC=CC(C#C)=C1
CAS DataBase Reference
766-81-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36/37/39
HS Code 
2903998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS007533
Product name
3′-bromophenyl acetylene
Purity
Aldrich<SUP>CPR</SUP>
Packaging
500 mg
Price
$185
Updated
2025/07/31
TCI Chemical
Product number
B5198
Product name
1-Bromo-3-ethynylbenzene
Purity
min. 98.0 %
Packaging
1G
Price
$127
Updated
2025/07/31
TCI Chemical
Product number
B5198
Product name
1-Bromo-3-ethynylbenzene
Purity
min. 98.0 %
Packaging
5G
Price
$380
Updated
2025/07/31
TRC
Product number
B700633
Product name
3-Bromophenylacetylene
Packaging
10mg
Price
$45
Updated
2021/12/16
Activate Scientific
Product number
AS48830
Product name
3-Bromophenylacetylene
Purity
98%
Packaging
1g
Price
$51
Updated
2021/12/16
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1-BROMO-3-ETHYNYL-BENZENE Chemical Properties,Usage,Production

Synthesis

3989-13-7

766-81-4

The general procedure for the synthesis of 3'-bromophenylacetylene from (3-bromophenylethynyl)trimethylsilane was as follows: intermediate 1-1 (166 g, 655.6 mmol) was dissolved in methanol (1000 mL) and placed in the reactor. Subsequently, potassium carbonate (90.6 g, 655.6 mmol) was added slowly and dropwise to the above solution. The reaction mixture was stirred at room temperature for about 30 minutes and then filtered. The filtrate was distilled under reduced pressure to remove the solvent and the residue was dissolved in ethyl acetate. This ethyl acetate solution was washed twice with distilled water to remove water soluble impurities. Finally, the organic solvent was removed by reduced pressure distillation to give intermediates 1-2 (116 g, 98% yield).

References

[1] Patent: US2018/339967, 2018, A1. Location in patent: Paragraph 0159; 0161
[2] Bioorganic and Medicinal Chemistry, 2010, vol. 18, # 2, p. 630 - 639
[3] European Journal of Organic Chemistry, 2010, # 33, p. 6323 - 6330
[4] Organic Letters, 2017, vol. 19, # 19, p. 5182 - 5185
[5] Patent: US2009/48320, 2009, A1. Location in patent: Page/Page column 62; 82

1-BROMO-3-ETHYNYL-BENZENE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BROMO-3-ETHYNYL-BENZENE Suppliers

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View Lastest Price from 1-BROMO-3-ETHYNYL-BENZENE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
3'-Bromophenyl acetylene 766-81-4
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%min
Supply Ability
100kg
Release date
2025-08-28
Hebei Xinsheng New Material Technology Co., LTD.
Product
1-BROMO-3-ETHYNYL-BENZENE 766-81-4
Price
US $35.00-25.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 Ton
Release date
2023-11-07
Hebei Xinsheng New Material Technology Co., LTD.
Product
1-BROMO-3-ETHYNYL-BENZENE 766-81-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
30000 Kg
Release date
2023-11-15

766-81-4, 1-BROMO-3-ETHYNYL-BENZENERelated Search:

Phenylacetylene 4-Bromophenylacetylene 3-(3-BROMOPHENYL)PROP-2-YN-1-OL 4-BROMO-2-ETHYNYL-6-METHOXY-PHENOL 1-BROMO-3-ETHYNYL-4-FLUORO-BENZENE 4-(3-BROMOPHENYL)-3-BUTYN-2-OL 3-BROMO-1-ETHYNYL-6-METHOXY-BENZENE 4-(3-BROMOPHENYL)-2-METHYL-3-BUTYN-2-OL (3-BROMOPHENYLETHYNYL)TRIMETHYLSILANE 2,4-DIBROMO-6-ETHYNYL-PHENYLAMINE N-(4-BROMO-2-TRIMETHYLSILANYLETHYNYL)-N'-(1,1DIETHYLAMINO)-DIAZENYLBENZENE 2,3-DIBROMO-4-ETHYNYL-6-METHOXY-PHENOL 2-BROMO-4-CHLORO-6-ETHYNYL-PHENOL BIS(3-BROMOPHENYL)ACETYLENE 1-BROMO-3-ETHYNYL-BENZENE 2,6-DIBROMO-4-ETHYNYL-PHENOL

  • 1-BROMO-3-ETHYNYL-BENZENE
  • 3'-BROMOPHENYL ACETYLENE
  • 3-BROMOPHENYLACETYLENE
  • Benzene, 1-broMo-3-ethynyl-
  • 3-Bromophenylacetylene - [B47527]
  • 766-81-4
  • Aromatic Halides (substituted)