1-BROMO-3-ETHYNYL-BENZENE
- Product Name
- 1-BROMO-3-ETHYNYL-BENZENE
- CAS No.
- 766-81-4
- Chemical Name
- 1-BROMO-3-ETHYNYL-BENZENE
- Synonyms
- 3-BROMOPHENYLACETYLENE;3'-BROMOPHENYL ACETYLENE;1-BROMO-3-ETHYNYL-BENZENE;Benzene, 1-broMo-3-ethynyl-;3-Bromophenylacetylene - [B47527]
- CBNumber
- CB6297455
- Molecular Formula
- C8H5Br
- Formula Weight
- 181.03
- MOL File
- 766-81-4.mol
1-BROMO-3-ETHYNYL-BENZENE Property
- Boiling point:
- 198.24°C (rough estimate)
- Density
- 1.4466
- refractive index
- 1.5896
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- Appearance
- Colorless to light yellow Liquid
- InChI
- InChI=1S/C8H5Br/c1-2-7-4-3-5-8(9)6-7/h1,3-6H
- InChIKey
- TZDXNFAAJNEYIO-UHFFFAOYSA-N
- SMILES
- C1(Br)=CC=CC(C#C)=C1
- CAS DataBase Reference
- 766-81-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36/37/39
- HS Code
- 2903998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CDS007533
- Product name
- 3′-bromophenyl acetylene
- Purity
- Aldrich<SUP>CPR</SUP>
- Packaging
- 500 mg
- Price
- $185
- Updated
- 2025/07/31
- Product number
- B5198
- Product name
- 1-Bromo-3-ethynylbenzene
- Purity
- min. 98.0 %
- Packaging
- 1G
- Price
- $127
- Updated
- 2025/07/31
- Product number
- B5198
- Product name
- 1-Bromo-3-ethynylbenzene
- Purity
- min. 98.0 %
- Packaging
- 5G
- Price
- $380
- Updated
- 2025/07/31
- Product number
- B700633
- Product name
- 3-Bromophenylacetylene
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B47527
- Product name
- 3-Bromophenylacetylene
- Purity
- 97%
- Packaging
- 100mg
- Price
- $15
- Updated
- 2021/12/16
1-BROMO-3-ETHYNYL-BENZENE Chemical Properties,Usage,Production
Synthesis
3989-13-7
766-81-4
The general procedure for the synthesis of 3'-bromophenylacetylene from (3-bromophenylethynyl)trimethylsilane was as follows: intermediate 1-1 (166 g, 655.6 mmol) was dissolved in methanol (1000 mL) and placed in the reactor. Subsequently, potassium carbonate (90.6 g, 655.6 mmol) was added slowly and dropwise to the above solution. The reaction mixture was stirred at room temperature for about 30 minutes and then filtered. The filtrate was distilled under reduced pressure to remove the solvent and the residue was dissolved in ethyl acetate. This ethyl acetate solution was washed twice with distilled water to remove water soluble impurities. Finally, the organic solvent was removed by reduced pressure distillation to give intermediates 1-2 (116 g, 98% yield).
References
[1] Patent: US2018/339967, 2018, A1. Location in patent: Paragraph 0159; 0161
[2] Bioorganic and Medicinal Chemistry, 2010, vol. 18, # 2, p. 630 - 639
[3] European Journal of Organic Chemistry, 2010, # 33, p. 6323 - 6330
[4] Organic Letters, 2017, vol. 19, # 19, p. 5182 - 5185
[5] Patent: US2009/48320, 2009, A1. Location in patent: Page/Page column 62; 82
1-BROMO-3-ETHYNYL-BENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
1-BROMO-3-ETHYNYL-BENZENE Suppliers
- Tel
- --
- Fax
- --
- Sales@casorganic.com
- Country
- Ukraine
- ProdList
- 5026
- Advantage
- 34
View Lastest Price from 1-BROMO-3-ETHYNYL-BENZENE manufacturers
- Product
- 3'-Bromophenyl acetylene 766-81-4
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 100kg
- Release date
- 2025-08-28
- Product
- 1-BROMO-3-ETHYNYL-BENZENE 766-81-4
- Price
- US $35.00-25.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 Ton
- Release date
- 2023-11-07
- Product
- 1-BROMO-3-ETHYNYL-BENZENE 766-81-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 30000 Kg
- Release date
- 2023-11-15