ChemicalBook > CAS DataBase List > Bremelanotide Acetate

Bremelanotide Acetate

Product Name: Bremelanotide Acetate
CAS No.: 1607799-13-2
Chemical Name: Bremelanotide Acetate
Synonyms: Pt141 Acetate;Bremelanotide, PT141, Acetate;Bremelanotide Acetate;189691-06-3 (free base);Validamine PT 141 Acetate;α-MSH (PT-141)，Bremelanotide;PT141 acetate (Bremelanotide);Bremelanotide acetate - Bio-X ?;Bremelanotide Acetate, 10 mM in DMSO;PT-141 ACETATE;189691-06-3 (FREE BASE)
CBNumber: CB63041389
Molecular Formula: C52H72N14O12
Formula Weight: 1085.23
MOL File: 1607799-13-2.mol

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Bremelanotide Acetate Property

storage temp.: Store at -20°C
solubility: DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 5 mg/ml
form: A solid
color: White to off-white
Sequence: Ac-[Nle}-Asp-His-{d-Phe}-Arg-Trp-Lys (Lactam bridge: Asp4-Lys7)
InChIKey: MAYUSRUHXFWITM-UKGCEBKRNA-N

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2756
Product name: Bremelanotide acetate
Purity: ≥98% (HPLC)
Packaging: 10MG
Price: $100
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML2756
Product name: Bremelanotide acetate
Purity: ≥98% (HPLC)
Packaging: 50MG
Price: $406
Updated: 2025/07/31

Biosynth Carbosynth

Product number: FB170950
Product name: Bremelanotide?acetate
Packaging: 10mg
Price: $55
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB170950
Product name: Bremelanotide?acetate
Packaging: 50mg
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB170950
Product name: Bremelanotide?acetate
Packaging: 100mg
Price: $220
Updated: 2021/12/16

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Bremelanotide Acetate Chemical Properties,Usage,Production

Description

Bremelanotide Acetate (PT-141 Acetate), a synthetic peptide analogue of α-MSH, is an agonist at melanocortin receptors including the MC3R and MC4R for the treatment of sexual dysfunction.. In Vivo: Bremelanotide Acetate (50-200 μg/kg; s.c.; once) significantly increases proceptive solicitations in females primed with Estradiol benzoate+Progesterone or Estradiol benzoate alone in bilevel chambers.

Uses

Bremelanotide is a novel drug candidate for the treatment of male and female sexual dysfunction. Bremelanotide has shown promise in effectively treating erectile dysfunction (ED) without the cardiovascular effects found in ED drugs currently available. Bremelanotide works through a mechanism of action involving the central nervous system rather than directly on the vascular system. As a result, it may offer significant safety and efficacy benefits over currently available products.

Mechanism of action

Bremelanotide Acetate works by activating melanocortin receptors in the central nervous system, primarily the melanocortin 4 receptor (MC4R). The melanocortin system is known to play a critical role in a variety of physiological processes, including energy homeostasis, inflammation, and sexual function.

Side effects

The most common adverse reactions reported include nausea, flushing, injection site reactions, and headache.

in vivo

Bremelanotide Acetate (50-200 μg/kg; s.c.; once) significantly increases proceptive solicitations in females primed with Estradiol benzoate+Progesterone or Estradiol benzoate alone in bilevel chambers^[2].

Animal Model:	Ovariectomized Long–Evans rats^[2]
Dosage:	50, 100, 200 μg/kg
Administration:	s.c.; once
Result:	Significantly increased proceptive solicitations in females primed with Estradiol benzoate+Progesterone or Estradiol benzoate alone in bilevel chambers.

IC 50

MC3R; MC4R

Bremelanotide Acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Bremelanotide Acetate manufacturers

TsurgeX Pharmaceutical Technology Co., Ltd.

Product: PT-141(Bremelanotide) 1607799-13-2
Price: US $279.35-167.61/g
Min. Order: 1g
Purity: 99%
Supply Ability: 1 tons
Release date: 2025-08-26

Ningbo Qingteng Plastic Cost.,Ltd.

Product: PT-141 Acetate 1607799-13-2
Price: US $20.00/box
Min. Order: 1box
Purity: 99
Supply Ability: in stock
Release date: 2025-07-31

Ningbo Qingteng Plastic Cost.,Ltd.

Product: Bremelanotide Acetate 1607799-13-2
Price: US $20.00/box
Min. Order: 1box
Purity: 99
Supply Ability: in stock
Release date: 2025-07-31

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1607799-13-2