ChemicalBook > CAS DataBase List > Centrinone

Centrinone

Product Name
Centrinone
CAS No.
1798871-30-3
Chemical Name
Centrinone
Synonyms
LCR-263;Centrinone;Centrinone (LCR-263);LCR 263,Polo-like Kinase (PLK),LCR263,Inhibitor,inhibit,Centrinone;2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol;2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-morpholinopyrimidin-4-amine;2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-4-pyrimidinamine;4-Pyrimidinamine, 2-[[2-fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-
CBNumber
CB63041394
Molecular Formula
C26H25F2N7O6S2
Formula Weight
633.65
MOL File
1798871-30-3.mol
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Centrinone Property

Melting point:
>187°C (dec.)
Boiling point:
924.2±75.0 °C(Predicted)
Density 
1.59±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Aqueous Base (Very Slightly), DMSO (Slightly)
form 
Solid
pka
13.65±0.10(Predicted)
color 
Off-White to Pale Brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris
Product number
5687
Product name
Centrinone
Purity
≥98%(HPLC)
Packaging
10
Price
$259
Updated
2021/12/16
TRC
Product number
C256613
Product name
Centrinone
Packaging
5mg
Price
$385
Updated
2021/12/16
ChemScene
Product number
CS-4921
Product name
Centrinone
Purity
98.57%
Packaging
5mg
Price
$144
Updated
2021/12/16
Crysdot
Product number
CD31002920
Product name
Centrinone
Purity
98+%
Packaging
10mg
Price
$166
Updated
2021/12/16
Crysdot
Product number
CD31002920
Product name
Centrinone
Purity
98+%
Packaging
5mg
Price
$101
Updated
2021/12/16
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Centrinone Chemical Properties,Usage,Production

Uses

Centrinone is a reversible inhibitor of Polo-like kinase 4 (Plk4), a serine-threonine protein kinase that initiates centriole assembly.

storage

Store at -20°C

Centrinone Preparation Products And Raw materials

Raw materials

Preparation Products

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Centrinone Suppliers

China 45 United Kingdom 1 United States 7 USA 1 Global 54
Shanghai Boyle Chemical Co., Ltd.
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Spectrum Chemical Manufacturing Corp.
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Amadis Chemical Company Limited
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Absin Bioscience Inc.
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Wuhan Topule
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1798871-30-3, CentrinoneRelated Search:


  • Centrinone
  • 2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-4-pyrimidinamine
  • 2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol
  • LCR-263
  • 4-Pyrimidinamine, 2-[[2-fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-
  • Centrinone (LCR-263)
  • LCR 263,Polo-like Kinase (PLK),LCR263,Inhibitor,inhibit,Centrinone
  • 2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-morpholinopyrimidin-4-amine
  • 1798871-30-3
  • C26H25F2N7O6S2