ChemicalBook > CAS DataBase List > Centrinone

Centrinone

Product Name
Centrinone
CAS No.
1798871-30-3
Chemical Name
Centrinone
Synonyms
LCR-263;Centrinone;Centrinone (LCR-263);LCR 263,Polo-like Kinase (PLK),LCR263,Inhibitor,inhibit,Centrinone;2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol;2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-morpholinopyrimidin-4-amine;2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-4-pyrimidinamine;4-Pyrimidinamine, 2-[[2-fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-
CBNumber
CB63041394
Molecular Formula
C26H25F2N7O6S2
Formula Weight
633.65
MOL File
1798871-30-3.mol
More
Less

Centrinone Property

Melting point:
>187°C (dec.)
Boiling point:
924.2±75.0 °C(Predicted)
Density 
1.59±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Aqueous Base (Very Slightly), DMSO (Slightly)
form 
Solid
pka
13.65±0.10(Predicted)
color 
Off-White to Pale Brown
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Tocris
Product number
5687
Product name
Centrinone
Purity
≥98%(HPLC)
Packaging
10
Price
$259
Updated
2021/12/16
TRC
Product number
C256613
Product name
Centrinone
Packaging
5mg
Price
$385
Updated
2021/12/16
ChemScene
Product number
CS-4921
Product name
Centrinone
Purity
98.57%
Packaging
5mg
Price
$144
Updated
2021/12/16
Crysdot
Product number
CD31002920
Product name
Centrinone
Purity
98+%
Packaging
5mg
Price
$101
Updated
2021/12/16
Crysdot
Product number
CD31002920
Product name
Centrinone
Purity
98+%
Packaging
10mg
Price
$166
Updated
2021/12/16
More
Less

Centrinone Chemical Properties,Usage,Production

Uses

Centrinone is a reversible inhibitor of Polo-like kinase 4 (Plk4), a serine-threonine protein kinase that initiates centriole assembly.

storage

Store at -20°C

Centrinone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1798871-30-3, CentrinoneRelated Search:


  • Centrinone
  • 2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-4-pyrimidinamine
  • 2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol
  • LCR-263
  • 4-Pyrimidinamine, 2-[[2-fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-
  • Centrinone (LCR-263)
  • LCR 263,Polo-like Kinase (PLK),LCR263,Inhibitor,inhibit,Centrinone
  • 2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-morpholinopyrimidin-4-amine
  • 1798871-30-3
  • C26H25F2N7O6S2