ChemicalBook > CAS DataBase List > Revefenacin

Revefenacin

Product Name
Revefenacin
CAS No.
864750-70-9
Chemical Name
Revefenacin
Synonyms
Revefenacin;TD-4208;1-(2-(4-((4-carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate;CPDD1221;REVENACIN;Refenaxin;GSK1160724;Raffinazine;TD 4208;TD4208;Revefenacin Crude
CBNumber
CB63054398
Molecular Formula
C35H43N5O4
Formula Weight
597.75
MOL File
864750-70-9.mol
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Revefenacin Property

Boiling point:
777.5±60.0 °C(Predicted)
Density 
1.26±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 125 mg/mL (209.12 mM)
form 
Solid
pka
13.34±0.70(Predicted)
color 
White to off-white
InChIKey
FYDWDCIFZSGNBU-UHFFFAOYSA-N
SMILES
C(OC1CCN(CCN(C(=O)C2=CC=C(CN3CCC(C(N)=O)CC3)C=C2)C)CC1)(=O)NC1=CC=CC=C1C1=CC=CC=C1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
464649
Product name
Revefenacin
Packaging
1mg
Price
$425
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0005717
Product name
TD-4208
Purity
95.00%
Packaging
5MG
Price
$500.2
Updated
2021/12/16
ChemScene
Product number
CS-7743
Product name
Revefenacin
Purity
99.78%
Packaging
2mg
Price
$120
Updated
2021/12/16
ChemScene
Product number
CS-7743
Product name
Revefenacin
Purity
99.78%
Packaging
5mg
Price
$192
Updated
2021/12/16
ChemScene
Product number
CS-7743
Product name
Revefenacin
Purity
99.78%
Packaging
10mg
Price
$312
Updated
2021/12/16
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Revefenacin Chemical Properties,Usage,Production

Description

Revefenacin is a synthetic anticholinergic that is prescribed for the treatment of chronic obstructive pulmonary disease (COPD).

Uses

Revefenacin is used to treat chronic obstructive pulmonary disease (COPD), a long-term (chronic) lung disease that includes chronic bronchitis, emphysema, or both. It is an anticholinergic drug that helps the muscles around the airways in the lungs stay relaxed to prevent symptoms such as wheezing, coughing, chest tightness, and shortness of breath.

Application

Revefenacin is an FDA-approved anticholinergic drug, a new tertiary amine biphenylcarbamate agent that also belongs to the long-acting muscarinic antagonist (LABA) family. It has the effect of relaxing the muscles around the airways of the lungs to make breathing easier. The structurally unstable tertiary amide produces a "soft drug" site, allowing rapid systemic clearance and minimising systemically mediated adverse effects. It can be used to treat symptoms such as wheezing, shortness of breath, cough and chest tightness in patients with chronic obstructive pulmonary disease (COPD: a group of diseases affecting the lungs and airways, including chronic bronchitis and emphysema).

brand name

Yupelri

Side effects

Common adverse reactions in clinical trials (1%-10%) were headache, nasopharyngitis, upper respiratory tract infection, back pain, bronchitis, dizziness, and hypertension.

Revefenacin Preparation Products And Raw materials

Raw materials

Preparation Products

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Revefenacin Suppliers

China 137 India 5 United States 7 Global 149
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View Lastest Price from Revefenacin manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Revefenacin 864750-70-9
Price
US $75.00-750.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-20
Biopole Pharmatech Co., Ltd.
Product
Revefenacin 864750-70-9
Price
US $0.00/g
Min. Order
1g
Purity
99.99%HPLC
Supply Ability
200kg
Release date
2024-02-04
Hangzhou ICH Biofarm Co., Ltd
Product
Revefenacin 864750-70-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.0%min
Supply Ability
800kg
Release date
2023-06-09

864750-70-9, RevefenacinRelated Search:

Kanamycin sulfate Dimethoxymethane ZVPVPYWMFMUFEZ-UHFFFAOYSA-N 1-(2-(methylamino)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate 1-(4-PIPERIDINYLCARBONYL)-4-PIPERIDINECARBOXYLIC ACID 1-(2-(methylamino)ethyl)piperidin-4-ol hydrochloride(WX191324S1) (Dimethylamino)acetaldehyde Dimethyl Acetal Carbamic acid, N-[1,1'-biphenyl]-2-yl-, 1-methyl-4-piperidinyl ester 1221

  • TD-4208
  • Revefenacin
  • Revefenacin / TD4208
  • GSK1160724
  • CPDD1221
  • Revefenacin:TD-4208:GSK-1160724
  • biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-ylester
  • TD 4208;TD4208
  • 1-(2-(4-((4-carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate
  • 1-[2-[[4-[(4-carbamoylpiperidin-1-yl)methyl]benzoyl]-methylamino]ethyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
  • Carbamic acid, N-[1,1'-biphenyl]-2-yl-, 1-[2-[[4-[[4-(aminocarbonyl)-1-piperidinyl]methyl]benzoyl]methylamino]ethyl]-4-piperidinyl ester
  • REVENACIN
  • Raffinazine
  • 1-[2-[[4-[[4-(Aminocarbonyl)-1-piperidinyl]methyl]benzoyl]methylamino]ethyl]-4-piperidinyl N-[1,1′-biphenyl]-2-ylcarbamate
  • Revefenacin Crude
  • 1-(2-(4-((4-Carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate
  • 1-(2-(3-((4-carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate
  • Refenaxin
  • 864750-70-9
  • C35H43N5O4