Revefenacin

Product Name: Revefenacin
CAS No.: 864750-70-9
Chemical Name: Revefenacin
Synonyms: Revefenacin;TD-4208;1-(2-(4-((4-carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate;CPDD1221;REVENACIN;Refenaxin;GSK1160724;Raffinazine;TD 4208;TD4208;Revefenacin Crude
CBNumber: CB63054398
Molecular Formula: C35H43N5O4
Formula Weight: 597.75
MOL File: 864750-70-9.mol

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Revefenacin Property

Boiling point:: 777.5±60.0 °C(Predicted)
Density: 1.26±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 125 mg/mL (209.12 mM)
form: Solid
pka: 13.34±0.70(Predicted)
color: White to off-white
InChIKey: FYDWDCIFZSGNBU-UHFFFAOYSA-N
SMILES: C(OC1CCN(CCN(C(=O)C2=CC=C(CN3CCC(C(N)=O)CC3)C=C2)C)CC1)(=O)NC1=CC=CC=C1C1=CC=CC=C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological

Product number: 464649
Product name: Revefenacin
Packaging: 1mg
Price: $425
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0005717
Product name: TD-4208
Purity: 95.00%
Packaging: 5MG
Price: $500.2
Updated: 2021/12/16

ChemScene

Product number: CS-7743
Product name: Revefenacin
Purity: 99.78%
Packaging: 2mg
Price: $120
Updated: 2021/12/16

ChemScene

Product number: CS-7743
Product name: Revefenacin
Purity: 99.78%
Packaging: 5mg
Price: $192
Updated: 2021/12/16

ChemScene

Product number: CS-7743
Product name: Revefenacin
Purity: 99.78%
Packaging: 10mg
Price: $312
Updated: 2021/12/16

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Revefenacin Chemical Properties,Usage,Production

Description

Revefenacin is a synthetic anticholinergic that is prescribed for the treatment of chronic obstructive pulmonary disease (COPD).

Uses

Revefenacin is used to treat chronic obstructive pulmonary disease (COPD), a long-term (chronic) lung disease that includes chronic bronchitis, emphysema, or both. It is an anticholinergic drug that helps the muscles around the airways in the lungs stay relaxed to prevent symptoms such as wheezing, coughing, chest tightness, and shortness of breath.

Application

Revefenacin is an FDA-approved anticholinergic drug, a new tertiary amine biphenylcarbamate agent that also belongs to the long-acting muscarinic antagonist (LABA) family. It has the effect of relaxing the muscles around the airways of the lungs to make breathing easier. The structurally unstable tertiary amide produces a "soft drug" site, allowing rapid systemic clearance and minimising systemically mediated adverse effects. It can be used to treat symptoms such as wheezing, shortness of breath, cough and chest tightness in patients with chronic obstructive pulmonary disease (COPD: a group of diseases affecting the lungs and airways, including chronic bronchitis and emphysema).

brand name

Yupelri

Side effects

Common adverse reactions in clinical trials (1%-10%) were headache, nasopharyngitis, upper respiratory tract infection, back pain, bronchitis, dizziness, and hypertension.

Revefenacin Preparation Products And Raw materials

Raw materials

Preparation Products

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Revefenacin Suppliers

China 137 India 5 United States 7 Global 149

Shandong Shengzhiyuan Biotechnology Co., LTD

Tel: 13589515191
Email: 513449328@qq.com
Country: China
ProdList: 120
Advantage: 58

Taizhou Tongxin Bio-Tech Co., Ltd

Tel: 0523-18601685-898 18652728585
Email: sales@allyrise.com
Country: China
ProdList: 2782
Advantage: 60

Nanjing Lift Pharmaceutical Technology Co., Ltd.

Tel: 18951933883
Fax: QQ:1665798899
Email: leo.feng@liftpharm.com
Country: China
ProdList: 308
Advantage: 58

Jinan Xinzheng Pharmaceutical Technology Co., Ltd.

Tel: 0531-88798968 18615218958
Email: yin3684895@126.com
Country: China
ProdList: 174
Advantage: 58

Chengdu Aupone Pharmaceutical Co.,Ltd.

Tel: 18980796919
Email: 236656639@qq.com
Country: China
ProdList: 23
Advantage: 58

HUBEI CHANGYAO BIOTECHNOLOGY CO LTD

Tel: 17683887209
Email: 906856569@qq.com
Country: China
ProdList: 4973
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

ZHIWE CHEMTECH CO LTD

Tel: 021-20221225 13917446399
Fax: QQ:115820162
Email: sales@zhiwe.net
Country: China
ProdList: 627
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

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View Lastest Price from Revefenacin manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Revefenacin 864750-70-9
Price: US $75.00-750.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-11-20

Biopole Pharmatech Co., Ltd.

Product: Revefenacin 864750-70-9
Price: US $0.00/g
Min. Order: 1g
Purity: 99.99%HPLC
Supply Ability: 200kg
Release date: 2024-02-04

Hangzhou ICH Biofarm Co., Ltd

Product: Revefenacin 864750-70-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.0%min
Supply Ability: 800kg
Release date: 2023-06-09

864750-70-9, RevefenacinRelated Search:

Kanamycin sulfate Dimethoxymethane ZVPVPYWMFMUFEZ-UHFFFAOYSA-N 1-(2-(methylamino)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate 1-(4-PIPERIDINYLCARBONYL)-4-PIPERIDINECARBOXYLIC ACID 1-(2-(methylamino)ethyl)piperidin-4-ol hydrochloride(WX191324S1) (Dimethylamino)acetaldehyde Dimethyl Acetal Carbamic acid, N-[1,1'-biphenyl]-2-yl-, 1-methyl-4-piperidinyl ester 1221

TD-4208

Revefenacin

Revefenacin / TD4208

GSK1160724

CPDD1221

Revefenacin:TD-4208:GSK-1160724

biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-ylester

TD 4208;TD4208

1-(2-(4-((4-carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate

1-[2-[[4-[(4-carbamoylpiperidin-1-yl)methyl]benzoyl]-methylamino]ethyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate

Carbamic acid, N-[1,1'-biphenyl]-2-yl-, 1-[2-[[4-[[4-(aminocarbonyl)-1-piperidinyl]methyl]benzoyl]methylamino]ethyl]-4-piperidinyl ester

REVENACIN

Raffinazine

1-[2-[[4-[[4-(Aminocarbonyl)-1-piperidinyl]methyl]benzoyl]methylamino]ethyl]-4-piperidinyl N-[1,1′-biphenyl]-2-ylcarbamate

Revefenacin Crude

1-(2-(4-((4-Carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate

1-(2-(3-((4-carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate

Refenaxin

864750-70-9

C35H43N5O4