MFCD00167693

Product Name: MFCD00167693
CAS No.: 199735-88-1
Chemical Name: MFCD00167693
Synonyms: HY-107999;MFCD00167693;CADD522, 10 mM in DMSO;3-(N-(3,4-DICHLOROPHENYL)CARBAMOYL)-5-NORBORNENE-2-CARBOXYLIC ACID;3-[(3,4-dichlorophenyl)carbamoyl]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid;3-{[(3,4-dichlorophenyl)amino]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid;Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-[[(3,4-dichlorophenyl)amino]carbonyl]-;inhibit,MDA-231,Inhibitor,Reactive Oxygen Species,CADD 522,MCF7,MDA-468,breast cancer,CADD522,T47D-RUNX2,CADD-522
CBNumber: CB63058321
Molecular Formula: C15H13Cl2NO3
Formula Weight: 326.17
MOL File: 199735-88-1.mol

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MFCD00167693 Property

Boiling point:: 569.1±50.0 °C(Predicted)
Density: 1.529±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO:157.5(Max Conc. mg/mL);482.87(Max Conc. mM)
Ethanol:65.0(Max Conc. mg/mL);199.28(Max Conc. mM)
form: A solid
pka: 4.19±0.40(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S720224
Product name: 3-(N-(3,4-DICHLOROPHENYL)CARBAMOYL)-5-NORBORNENE-2-CARBOXYLIC ACID
Purity: AldrichCPR
Packaging: 50MG
Price: $110
Updated: 2024/03/01

Matrix Scientific

Product number: 159610
Product name: 3-{[(3,4-Dichlorophenyl)amino]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
Packaging: 0.500g
Price: $120
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD136060
Product name: 3-{[(3,4-Dichlorophenyl)amino]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
Packaging: 1g
Price: $128
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD136060
Product name: 3-{[(3,4-Dichlorophenyl)amino]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 159610
Product name: 3-{[(3,4-Dichlorophenyl)amino]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
Packaging: 1g
Price: $150
Updated: 2021/12/16

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MFCD00167693 Chemical Properties,Usage,Production

Uses

CADD522 is a potent inhibitor of RUNX2(runt-related transcription factor-2)-DNA.

Biological Activity

CADD522 is a cell-permeable, bioavailable, non-toxic carbamoyl-bicycloheptene-carboxylate th at inhibits RUNX2-DNA binding, thereby increases RUNX2 stability, upregulates RUNX2 expression levels and downregulates RUNX2 responsive genes transcription. CADD522 inhibits mitochondrial oxidative phosphorylation by decreasing the mitochondrial oxygen consumption rate and ATP production in human breast cancer cells in a RUNX2-independent manner. CADD-522 suppresses in vivo tumor growth and metastasis, and appreciably prolongs the survival rates without the need for surgery or chemotherapy.

MFCD00167693 Preparation Products And Raw materials

Raw materials

Preparation Products

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MFCD00167693 Suppliers

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199735-88-1, MFCD00167693Related Search:

CHLOROPHENYLSILANE 97 Dichloromethylphenylsilane Phenylsilane Benzeneruthenium(II) chloride dimer Phenyltrichlorosilane

MFCD00167693

3-{[(3,4-dichlorophenyl)amino]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid

HY-107999

Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-[[(3,4-dichlorophenyl)amino]carbonyl]-

inhibit,MDA-231,Inhibitor,Reactive Oxygen Species,CADD 522,MCF7,MDA-468,breast cancer,CADD522,T47D-RUNX2,CADD-522

3-[(3,4-dichlorophenyl)carbamoyl]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid

CADD522, 10 mM in DMSO

3-(N-(3,4-DICHLOROPHENYL)CARBAMOYL)-5-NORBORNENE-2-CARBOXYLIC ACID

199735-88-1