ChemicalBook > CAS DataBase List > Br-PEG1-COOtBu

Br-PEG1-COOtBu

Product Name: Br-PEG1-COOtBu
CAS No.: 1393330-36-3
Chemical Name: Br-PEG1-COOtBu
Synonyms: Br-PEG1-COOtBu;CAS_1393330-36-3;Bromo-PEG1-C2-Boc;Br-PEG1-CH2CH2COOtBu;Bromo-PEG1-t-butyl ester;Bromo-PEG1-tert-butyl Ester;tert-Butyl 3-(2-bromoethoxy)propanoate;Propanoic acid, 3-(2-bromoethoxy)-, 1,1-dimethylethyl ester
CBNumber: CB63062438
Molecular Formula: C9H17BrO3
Formula Weight: 253.13
MOL File: 1393330-36-3.mol

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Br-PEG1-COOtBu Property

Boiling point:: 285.0±15.0 °C(Predicted)
Density: 1.264±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in DCM, Hexane
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C9H17BrO3/c1-9(2,3)13-8(11)4-6-12-7-5-10/h4-7H2,1-3H3
InChIKey: KRGOEVTUVNSLIG-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)CCOCCBr

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P313Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B750705
Product name: Bromo-PEG1-t-butylEster
Packaging: 50mg
Price: $265
Updated: 2021/12/16

AK Scientific

Product number: 8402DP
Product name: Bromo-PEG1-t-butylester
Packaging: 5g
Price: $2444
Updated: 2021/12/16

BroadPharm

Product number: BP-20900
Product name: Bromo-PEG1-t-butylester
Purity: 98%
Packaging: 250mg
Price: $380
Updated: 2021/12/16

AK Scientific

Product number: 8402DP
Product name: Bromo-PEG1-t-butylester
Packaging: 250mg
Price: $464
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1347
Product name: Bromo-PEG1-t-butyl ester
Packaging: 250mg
Price: $546
Updated: 2021/12/16

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Br-PEG1-COOtBu Chemical Properties,Usage,Production

Description

Bromo-PEG1-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Bromo-PEG1-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Br-PEG1-COOtBu Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Br-PEG1-COOtBu manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Br-PEG1-COOtBu 1393330-36-3
Price: US $0.00/g
Min. Order: 10g
Purity: >98.00%
Supply Ability: 10g
Release date: 2024-03-25

Career Henan Chemical Co

Product: Bromo-PEG1-t-butyl ester 1393330-36-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-21

Career Henan Chemical Co

Product: Bromo-PEG1-t-butyl ester 1393330-36-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-21

1393330-36-3, Br-PEG1-COOtBuRelated Search:

Bromo-PEG3-t-butyl ester 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo- Br-PEG3-CH2CO2H 1,14-DIBROMO-3,6,9,12-TETRAOXATETRADECANE Bromo-PEG4-acid Bromo-PEG2-acid Bromo-PEG2-t-butyl ester Diethyl bromodifluoromethanephosphonate Bromoacetaldehyde diethyl acetal (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide tert-Butyl (2-(2-bromoethoxy)ethyl)carbamate Bromo-PEG1-CH2CO2H Bromo-PEG2-NH2 HBr Bromo-PEG1-Acid Br-PEG7-Br Bromo-PEG8-azide Bromo-PEG4-t-butyl ester Ethanol, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1-methanesulfonate

Bromo-PEG1-t-butyl ester

tert-Butyl 3-(2-bromoethoxy)propanoate

CAS_1393330-36-3

Propanoic acid, 3-(2-bromoethoxy)-, 1,1-dimethylethyl ester

Bromo-PEG1-C2-Boc

Br-PEG1-CH2CH2COOtBu

Bromo-PEG1-tert-butyl Ester

Br-PEG1-COOtBu

1393330-36-3