INT-131

Product Name: INT-131
CAS No.: 315224-26-1
Chemical Name: INT-131
Synonyms: T-131;CHS 131;INT-131;T-0903131;Ibrigampar;AMG131, 10 mM in DMSO;N-(3,5-DICHLORO-4-QUINOLIN-3-YLOXYPHENYL)-2,4-DIHYDROXYBENZENESULFONAMIDE;2,4-dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide;Benzenesulfonamide, 2,4-dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]-;AMG131,proliferator,inhibit,Inhibitor,activated,Peroxisome proliferator-activated receptors,INT 131,mellitus,peroxisome,PPARγ,diabetes,INT131,AMG 131,PPAR,receptor,SPPARM,T2DM
CBNumber: CB63145568
Molecular Formula: C21H12Cl4N2O3S
Formula Weight: 514.21
MOL File: 315224-26-1.mol

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INT-131 Property

Boiling point:: 611.8±65.0 °C(Predicted)
Density: 1.585±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 250 mg/mL (486.18 mM; Need ultrasonic)
form: Solid
pka: 5.30±0.10(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2918
Product name: INT131
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $107
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2918
Product name: INT131
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $344
Updated: 2024/03/01

Atlantic Research Chemicals

Product number: XS0011551
Product name: 2,4-Dichloro-N-[3,5-dichloro-4-(quinolin-3-yloxy)phenyl]benzenesulfonamide
Purity: 95%
Packaging: 1gm:
Price: $1410.29
Updated: 2021/12/16

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INT-131 Chemical Properties,Usage,Production

Biological Activity

INT131 is a brain penetrant, non-thiazolidinedione, highly potent and selective peroxisome proliferator-activated receptor gamma (PPARγ) modulator (SPPARM) th at displays anti-diabetic activities. INT131 is a partial, rather than a full agonist of PPARγ, and in clinical trials has shown increased glucose tolerance without the weight gain and cardiovascular side effects seen with some of the full agonist.

storage

Store at -20°C

INT-131 Preparation Products And Raw materials

Raw materials

Preparation Products

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INT-131 Suppliers

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315224-26-1, INT-131Related Search:

INT-131

N-(3,5-DICHLORO-4-QUINOLIN-3-YLOXYPHENYL)-2,4-DIHYDROXYBENZENESULFONAMIDE

2,4-dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide

Benzenesulfonamide, 2,4-dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]-

CHS 131

AMG131,proliferator,inhibit,Inhibitor,activated,Peroxisome proliferator-activated receptors,INT 131,mellitus,peroxisome,PPARγ,diabetes,INT131,AMG 131,PPAR,receptor,SPPARM,T2DM

Ibrigampar

T-0903131

T-131

AMG131, 10 mM in DMSO

315224-26-1

C21H12Cl4N2O3S