ChemicalBook > CAS DataBase List > INT-131
INT-131
- Product Name
- INT-131
- CAS No.
- 315224-26-1
- Chemical Name
- INT-131
- Synonyms
- T-131;CHS 131;INT-131;T-0903131;Ibrigampar;AMG131, 10 mM in DMSO;N-(3,5-DICHLORO-4-QUINOLIN-3-YLOXYPHENYL)-2,4-DIHYDROXYBENZENESULFONAMIDE;2,4-dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide;Benzenesulfonamide, 2,4-dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]-;AMG131,proliferator,inhibit,Inhibitor,activated,Peroxisome proliferator-activated receptors,INT 131,mellitus,peroxisome,PPARγ,diabetes,INT131,AMG 131,PPAR,receptor,SPPARM,T2DM
- CBNumber
- CB63145568
- Molecular Formula
- C21H12Cl4N2O3S
- Formula Weight
- 514.21
- MOL File
- 315224-26-1.mol
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INT-131 Property
- Boiling point:
- 611.8±65.0 °C(Predicted)
- Density
- 1.585±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 250 mg/mL (486.18 mM; Need ultrasonic)
- form
- Solid
- pka
- 5.30±0.10(Predicted)
- color
- White to light yellow
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML2918
- Product name
- INT131
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $107
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML2918
- Product name
- INT131
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $344
- Updated
- 2024/03/01
Atlantic Research Chemicals
- Product number
- XS0011551
- Product name
- 2,4-Dichloro-N-[3,5-dichloro-4-(quinolin-3-yloxy)phenyl]benzenesulfonamide
- Purity
- 95%
- Packaging
- 1gm:
- Price
- $1410.29
- Updated
- 2021/12/16
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INT-131 Chemical Properties,Usage,Production
Biological Activity
INT131 is a brain penetrant, non-thiazolidinedione, highly potent and selective peroxisome proliferator-activated receptor gamma (PPARγ) modulator (SPPARM) th at displays anti-diabetic activities. INT131 is a partial, rather than a full agonist of PPARγ, and in clinical trials has shown increased glucose tolerance without the weight gain and cardiovascular side effects seen with some of the full agonist.
storage
Store at -20°C
INT-131 Preparation Products And Raw materials
Raw materials
Preparation Products
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