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INT-131

Product Name
INT-131
CAS No.
315224-26-1
Chemical Name
INT-131
Synonyms
T-131;CHS 131;INT-131;T-0903131;Ibrigampar;AMG131, 10 mM in DMSO;N-(3,5-DICHLORO-4-QUINOLIN-3-YLOXYPHENYL)-2,4-DIHYDROXYBENZENESULFONAMIDE;2,4-dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide;Benzenesulfonamide, 2,4-dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]-;AMG131,proliferator,inhibit,Inhibitor,activated,Peroxisome proliferator-activated receptors,INT 131,mellitus,peroxisome,PPARγ,diabetes,INT131,AMG 131,PPAR,receptor,SPPARM,T2DM
CBNumber
CB63145568
Molecular Formula
C21H12Cl4N2O3S
Formula Weight
514.21
MOL File
315224-26-1.mol
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INT-131 Property

Boiling point:
611.8±65.0 °C(Predicted)
Density 
1.585±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 250 mg/mL (486.18 mM; Need ultrasonic)
form 
Solid
pka
5.30±0.10(Predicted)
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2918
Product name
INT131
Purity
≥98% (HPLC)
Packaging
5MG
Price
$107
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2918
Product name
INT131
Purity
≥98% (HPLC)
Packaging
25MG
Price
$344
Updated
2024/03/01
Atlantic Research Chemicals
Product number
XS0011551
Product name
2,4-Dichloro-N-[3,5-dichloro-4-(quinolin-3-yloxy)phenyl]benzenesulfonamide
Purity
95%
Packaging
1gm:
Price
$1410.29
Updated
2021/12/16
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INT-131 Chemical Properties,Usage,Production

Biological Activity

INT131 is a brain penetrant, non-thiazolidinedione, highly potent and selective peroxisome proliferator-activated receptor gamma (PPARγ) modulator (SPPARM) th at displays anti-diabetic activities. INT131 is a partial, rather than a full agonist of PPARγ, and in clinical trials has shown increased glucose tolerance without the weight gain and cardiovascular side effects seen with some of the full agonist.

storage

Store at -20°C

INT-131 Preparation Products And Raw materials

Raw materials

Preparation Products

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INT-131 Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
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55
Wuhan TCASChem Technology Co., Ltd.
Tel
027-027-86697669 13986148687
Fax
86-027-86697669
Email
sales@tcaschem.com
Country
China
ProdList
3890
Advantage
55
Struchem Co., Ltd.
Tel
0512-0512-63009836 15365350169
Fax
0512-63006936
Email
helen@struchem.com
Country
China
ProdList
3984
Advantage
60
ATK CHEMICAL COMPANY LIMITED
Tel
021-51619050 13301662590
Fax
+86-21-51619052
Email
mandy@atkchemical.com
Country
China
ProdList
7776
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9805
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7312
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58
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
Country
China
ProdList
9987
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Chongqing Chemieliva Pharmaceutical Co., Ltd.
Tel
023-67770219
Fax
+86 (23) 6777-0220
Email
jessica.hu@chemieliva.com
Country
China
ProdList
1469
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60

315224-26-1, INT-131Related Search:


  • INT-131
  • N-(3,5-DICHLORO-4-QUINOLIN-3-YLOXYPHENYL)-2,4-DIHYDROXYBENZENESULFONAMIDE
  • 2,4-dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide
  • Benzenesulfonamide, 2,4-dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]-
  • CHS 131
  • AMG131,proliferator,inhibit,Inhibitor,activated,Peroxisome proliferator-activated receptors,INT 131,mellitus,peroxisome,PPARγ,diabetes,INT131,AMG 131,PPAR,receptor,SPPARM,T2DM
  • Ibrigampar
  • T-0903131
  • T-131
  • AMG131, 10 mM in DMSO
  • 315224-26-1
  • C21H12Cl4N2O3S