SMURF1 inhibitor A01

Product Name: SMURF1 inhibitor A01
CAS No.: 1007647-73-5
Chemical Name: SMURF1 inhibitor A01
Synonyms: A01;Smurf1-IN-A01;SMURF1 inhibitor A01;SMURF1 inhibitor A01 - A01;Smurf1-IN-A01, 10 mM in DMSO;A01 (Smurf1 inhibitor) >=98% (HPLC);Inhibitor,Smurf1 IN A01,inhibit,Smurf1INA01,A-01,Smurf-1-IN-A01,A 01;[4-[[4-Chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]methanone;(4-((4-Chloro-3-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)(4-(5-methyl-1H-pyrazol-1-yl)phenyl)methanone;Methanone, [4-[[4-chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]-
CBNumber: CB63146383
Molecular Formula: C22H20ClF3N4O3S
Formula Weight: 512.93
MOL File: 1007647-73-5.mol

More

Less

SMURF1 inhibitor A01 Property

Boiling point:: 642.3±65.0 °C(Predicted)
Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO : 62.5 mg/mL (121.85 mM; Need ultrasonic)
form: A crystalline solid
pka: 0.80±0.10(Predicted)
color: Light yellow to yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 26137
Product name: A01
Packaging: 5mg
Price: $97
Updated: 2024/03/01

Cayman Chemical

Product number: 26137
Product name: A01
Packaging: 50mg
Price: $577
Updated: 2024/03/01

Cayman Chemical

Product number: 26137
Product name: A01
Packaging: 10mg
Price: $175
Updated: 2024/03/01

Cayman Chemical

Product number: 26137
Product name: A01
Packaging: 25mg
Price: $360
Updated: 2024/03/01

Tocris

Product number: 5397
Product name: A01
Purity: ≥98%(HPLC)
Packaging: 10
Price: $168
Updated: 2021/12/16

More

Less

SMURF1 inhibitor A01 Chemical Properties,Usage,Production

Uses

A01 is a microlmolecule inhibitor of negatively regulatory factor Smurf1 for promoting bone formation.

Biological Activity

A01 is a high affinity selective inhibitor of E3 ubiquitin-protein ligase Smurf1 (Smad ubiquitination regulatory factor-1) th at disturbs Smurf1-Smad1/5 interaction and blocks Smurf1 mediated Smad1/5 ubiquitination. A01 increases responsiveness to BMP-2 in myoblasts and osteoblasts.

storage

Store at +4°C

SMURF1 inhibitor A01 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

SMURF1 inhibitor A01 Suppliers

China 44 United Kingdom 1 United States 5 USA 1 Global 51

Tocris Bioscience

Tel: --
Fax: --
Email: customerservice@tocris.co.uk
Country: United Kingdom
ProdList: 5726
Advantage: 77

1007647-73-5, SMURF1 inhibitor A01Related Search:

SMURF1 inhibitor A01

SMURF1 inhibitor A01 - A01

Smurf1-IN-A01

A01

[4-[[4-Chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]methanone

Methanone, [4-[[4-chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]-

A01 (Smurf1 inhibitor) >=98% (HPLC)

(4-((4-Chloro-3-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)(4-(5-methyl-1H-pyrazol-1-yl)phenyl)methanone

Inhibitor,Smurf1 IN A01,inhibit,Smurf1INA01,A-01,Smurf-1-IN-A01,A 01

Smurf1-IN-A01, 10 mM in DMSO

1007647-73-5

C22H20ClF3N4O3S