Azido-PEG3-S-PEG4-t-butyl ester
- Product Name
- Azido-PEG3-S-PEG4-t-butyl ester
- CAS No.
- 2055041-19-3
- Chemical Name
- Azido-PEG3-S-PEG4-t-butyl ester
- Synonyms
- Azido-PEG3-S-PEG4-t-butyl ester;tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethylsulfanyl]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
- CBNumber
- CB63162871
- Molecular Formula
- C23H45N3O9S
- Formula Weight
- 539.69
- MOL File
- 2055041-19-3.mol
N-Bromosuccinimide Price
- Product number
- BP-23190
- Product name
- Azido-PEG3-S-PEG4-t-butylester
- Purity
- 98%
- Packaging
- 100mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- BP-23190
- Product name
- Azido-PEG3-S-PEG4-t-butylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- BP-23190
- Product name
- Azido-PEG3-S-PEG4-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $750
- Updated
- 2021/12/16
- Product number
- BP-23190
- Product name
- Azido-PEG3-S-PEG4-t-butylester
- Purity
- 98%
- Packaging
- 1g
- Price
- $1400
- Updated
- 2021/12/16
Azido-PEG3-S-PEG4-t-butyl ester Chemical Properties,Usage,Production
Description
Azido-PEG3-S-PEG4-t-butyl ester is a PEG linker containing one azide group and one t-butyl protected carboxyl group. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group (COOH) prevents self coupling or polymerization under standard acid/amine or acid/hydroxyl coupling conditions.
Uses
Azido-PEG3-S-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-S-PEG4-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG3-S-PEG4-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG3-S-PEG4-t-butyl ester Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
View Lastest Price from Azido-PEG3-S-PEG4-t-butyl ester manufacturers
- Product
- Azido-PEG3-S-PEG4-t-butyl ester 2055041-19-3
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >95.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-28