ChemicalBook > CAS DataBase List > 2,2'-DIHYDROXYCHALCONE
2,2'-DIHYDROXYCHALCONE
- Product Name
- 2,2'-DIHYDROXYCHALCONE
- CAS No.
- 15131-80-3
- Chemical Name
- 2,2'-DIHYDROXYCHALCONE
- Synonyms
- 2,2'-Dihydroxychalcone;2,2'-Dihydroxychalcone;2,2'-Dihydroxychalchone;2,2''-DIHYDROXYCHALCHONE;2,2''-Dihydroxy chalcone;trans-2,2'-dihydroxychalcone;1,3-bis(2-hydroxyphenyl)-2-propen-1-on;1,3-DI(2-HYDROXYPHENYL)PROP-2-EN-1-ONE;Chalcone, 2,2'-dihydroxy- (6ci,7ci,8ci);1,3-bis(2-hydroxyphenyl)-2-propen-1-one
- CBNumber
- CB6318442
- Molecular Formula
- C15H12O3
- Formula Weight
- 240.25
- MOL File
- 15131-80-3.mol
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2,2'-DIHYDROXYCHALCONE Property
- Melting point:
- 161-162°C
- Boiling point:
- 447.1±45.0 °C(Predicted)
- Density
- 1.286±0.06 g/cm3(Predicted)
- pka
- 7.72±0.30(Predicted)
- form
- solid
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Safety
- RIDADR
- UN 2811 6.1 / PGIII
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- IDF00045
- Product name
- 2,2′-Dihydroxychalcone
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $179
- Updated
- 2025/07/31
TRC
- Product number
- D452863
- Product name
- 2,2''-Dihydroxychalcone
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FD66599
- Product name
- 2,2'-Dihydroxychalcone
- Packaging
- 2g
- Price
- $75
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FD66599
- Product name
- 2,2'-Dihydroxychalcone
- Packaging
- 5G
- Price
- $125
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FD66599
- Product name
- 2,2'-Dihydroxychalcone
- Packaging
- 10g
- Price
- $200
- Updated
- 2021/12/16
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2,2'-DIHYDROXYCHALCONE Chemical Properties,Usage,Production
Uses
2,2′-Dihydroxychalcone, a flavonoid, is a glutathione S-transferase (GST) inhibitor with an IC50 of 28.9 μM in human colon cancer cells. 2,2′-Dihydroxychalcone induces cell cycle arrest and apoptosis in prostate cancer cells. 2,2′-Dihydroxychalcone has anticancer and anti-inflammatory properties[1][2].
References
[1] Ahmed Q Haddad, et al. Antiproliferative mechanisms of the flavonoids 2,2'-dihydroxychalcone and fisetin in human prostate cancer cells. Nutr Cancer. 2010;62(5):668-81. DOI:10.1080/01635581003605524
[2] Kenneth Goh, et al. 2,2'-Dihydroxychalcone, a glutathione transferase inhibitor, sensitises human colon adenocarcinoma cells to chlorambucil and melphalan, but not to actinomycin D. Mol Med Rep. 2008 Jul-Aug;1(4):575-9. PMID:21479453
2,2'-DIHYDROXYCHALCONE Preparation Products And Raw materials
Raw materials
Preparation Products
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15131-80-3, 2,2'-DIHYDROXYCHALCONERelated Search:
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2',4'-DIHYDROXYCHALCONE
[(E)-2',4'-Dihydroxychalcone-4-yl]β-D-glucopyranoside
4,2'-DIHYDROXYCHALCONE,2',4-DIHYDROXYCHALCONE
DHF
5,2'-DIMETHOXYFLAVONE
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2'-HYDROXY-2-METHOXYCHALCONE
3,2'-DIMETHOXYFLAVONE
6,2'-DIMETHOXYFLAVONE
5,2'-DIHYDROXYFLAVONE
4,4'-Dihydroxychalcone, 4-Methyl ether