N-Methylcyclohexylamine Property

Melting point:

-9--7 °C (lit.)

Boiling point:

149 °C (lit.)

Density 

0.868 g/mL at 25 °C (lit.)

vapor density 

4 (vs air)

vapor pressure 

11 mm Hg ( 40 °C)

refractive index 

n20/D 1.456(lit.)

Flash point:

85 °F

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

54g/l

form 

Liquid

pka

11.03±0.20(Predicted)

Specific Gravity

0.855 (20/4℃)

color 

Clear colorless to yellow

PH

12 (10g/l, H2O, 20℃)

explosive limit

2.2-10.5%(V)

Water Solubility 

5.4 g/100 mL (20 ºC)

Sensitive 

Air Sensitive

BRN 

1523664

Dielectric constant

3.6400000000000001

CAS DataBase Reference

100-60-7(CAS DataBase Reference)

NIST Chemistry Reference

Cyclohexanamine, N-methyl-(100-60-7)

EPA Substance Registry System

Cyclohexanamine, N-methyl- (100-60-7)

Safety

Hazard Codes 

C

Risk Statements 

10-21/22-35-20/21/22

Safety Statements 

16-26-36/37/39-45

RIDADR 

UN 2734 8/PG 2

WGK Germany 

1

RTECS 

GX1529000

Hazard Note 

Corrosive

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29213099

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H290May be corrosive to metals

H302Harmful if swallowed

H311Toxic in contact with skin

H314Causes severe skin burns and eye damage

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

N-Methylcyclohexylamine Chemical Properties,Usage,Production

Chemical Properties

clear colourless to yellow liquid

Uses

Intermediate, solvent, acid acceptor.

Uses

N-Methylcyclohexanamine is a chemical reagent used in the synthesis of Mps1 kinase inhibitors used in cancer research. Also used in the synthesis of antituberculosis agents as indole-2-carboxamides.

Uses

N-Methylcyclohexylamine is used as a component of vulcanization accelerators, but the market size is relatively small.

Preparation

N-Methylcyclohexylamine can be prepared by a procedure similar to that used for cyclohexylamine, i.e., by hydrogenation of methylaniline over a supported nickel catalyst or from cyclohexanone and methylamine under hydrogenation conditions. Cyclohexylamine reacts with methanol over copper, zinc, or copper – calcium catalysts.

Definition

ChEBI: A secondary aliphatic amine having methyl and cyclohexyl as the two alkyl groups.

General Description

A water-white liquid. Slightly soluble in water and floats on water. A strong irritant to skin and eyes. Corrosive. Used as a solvent.

Air & Water Reactions

Flammable. Slightly soluble in water.

Reactivity Profile

METHYL CYCLOHEXYLAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Hazard

Toxic. Strong irritant to tissue.

Health Hazard

May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.