Imazamox
Description References- Product Name
- Imazamox
- CAS No.
- 114311-32-9
- Chemical Name
- Imazamox
- Synonyms
- 2-(4-Isopropyl-4-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)-5-(methoxymethyl)nicotinic acid;RPTOR;Raptor;Sweeper;Odyseey;CL29926;IMAZAMOX;AC299263;KIAA1303;CL 299263
- CBNumber
- CB6333049
- Molecular Formula
- C15H19N3O4
- Formula Weight
- 305.33
- MOL File
- 114311-32-9.mol
Imazamox Property
- Melting point:
- 166-167°C
- Density
- 1.39 g/cm3
- storage temp.
- 0-6°C
- solubility
- DMSO : 20 mg/mL (65.50 mM)
- pka
- pK1 2.3; pK2 3.3(at 25℃)
- InChI
- InChI=1S/C15H19N3O4/c1-8(2)15(3)14(21)17-12(18-15)11-10(13(19)20)5-9(6-16-11)7-22-4/h5-6,8H,7H2,1-4H3,(H,19,20)(H,17,18,21)
- InChIKey
- NUPJIGQFXCQJBK-UHFFFAOYSA-N
- SMILES
- C1(C2NC(=O)C(C)(C(C)C)N=2)=NC=C(COC)C=C1C(O)=O
- CAS DataBase Reference
- 114311-32-9(CAS DataBase Reference)
- EPA Substance Registry System
- Imazamox (114311-32-9)
Safety
- Hazard Codes
- N
- Risk Statements
- 50/53
- Safety Statements
- 60-61
- RIDADR
- UN3077 9/PG 3
- WGK Germany
- 3
- Hazardous Substances Data
- 114311-32-9(Hazardous Substances Data)
- Toxicity
- LD50 (technical grade) orally in rats: >5000 mg/kg; dermally in rabbits: >4000 mg/kg; LC50 by inhalation in rats: >6.3 mg/l (Glover)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SAB1305088
- Product name
- ANTI-PHOSPHO-RAPTOR(S863) antibody produced in rabbit
- Purity
- affinity isolated antibody, buffered aqueous solution
- Packaging
- 400μl
- Price
- $481
- Updated
- 2024/03/01
- Product number
- 34227
- Product name
- Imazamox
- Purity
- PESTANAL
- Packaging
- 100mg
- Price
- $150
- Updated
- 2024/03/01
- Product number
- I268550
- Product name
- Imazamox
- Packaging
- 10g
- Price
- $580
- Updated
- 2021/12/16
- Product number
- R1170-02B-AP
- Product name
- Raptor
- Packaging
- 200ul
- Price
- $711
- Updated
- 2021/12/16
- Product number
- PST0000158
- Product name
- IMAZAMOX
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $909.56
- Updated
- 2021/12/16
Imazamox Chemical Properties,Usage,Production
Description
Imazamox (2-[4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-5- (methoxymethyl)-3-pyridinecarboxylic acid) is a systemic herbicide that moves throughout the plant tissue and prevents plants from producing a necessary enzyme, acetolactate synthase (ALS), which is not found in animals. Susceptible plants will stop growing soon after treatment, but plant death and decomposition will occur over several weeks.
Imazamox is used for the control of vegetation in and around aquatic sites and terrestrial non-crop sites. It is herbicidally active on many submerged, emergent, and floating broadleaf and monocot aquatic plants in and around standing and slow- moving water bodies. It is used as herbicide on sunflower seed, alfalfa, oilseed rape and soya bean seed and used for the control of most annual and perennial broadleaf weeds and grasses, woody species, and riparian and emergent aquatic weed species.
Imazamox is only moderately persistent, and it degrades aerobically in the soil to a non-herbicidal metabolite which is immobile or moderately mobile. Imazamox also degrades by aqueous photolysis.
References
[1] http://dnr.wi.gov/lakes/plants/factsheets/ImazamoxFactsheet.pdf
[2] https://www.efsa.europa.eu/en/efsajournal/pub/4432
[3] http://www.mass.gov/eea/docs/agr/pesticides/aquatic/imazamox.pdf
Description
Imazamox is registered throughout the world for use in leguminous crops, including soybeans, alfalfa, and edible beans, as well as in imidazolinone-resistant crops (9). A nonionic surfactant or oil adjuvant is required for maximum activity. Imazamox is much more active when applied post-emergent to the weeds compared with pre-emergence application (9). One difference between imazamox and other imidazolinones is the much shorter interval needed before sensitive follow crops can be planted. This difference is due to the more rapid degradation of imazamox in the soil compared with other imidazolinones.
Chemical Properties
Off-White Solid
Uses
Imazamox is an imidazolinone based acetolactate synthase inhibitor that is utilized as a herbicide for weed control.
Uses
Herbicide.
Definition
ChEBI: 2-(4-isopropyl-4-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)-5-(methoxymethyl)nicotinic acid is a pyridinemonocarboxylic acid that is nicotinic acid which is substituted substituted at position 5 by a methoxymethyl group and at position 2 by a 4,5-dihydro-1H-imidazol-2-yl group, that in turn is substituted by isopropyl, methyl, and oxo groups at positions 4, 4, and 5, respectively. It is a pyridinemonocarboxylic acid, an ether, an imidazolone and a member of imidazolines.
Pharmacology
Imazamox kills plants by inhibiting acetolactate synthase (ALS) (I50 = 1 μM), which is the first common enzyme in the biosynthesis of the branched chain amino acids, valine, leucine, and isoleucine. Imazamox is rapidly absorbed through the leaves of plants. Once it enters the plant, imazamox rapidly translocates to the growing points and growth ceases within 1 day after herbicide application, followed by chlorosis and then by necrosis of the growing points. Total plant death will occur within 2 to 3 weeks after treatment.
Metabolism
Plant Metabolism. The selectivity of imazamox is due to
differential rates and routes of metabolism in tolerant
crops versus susceptible weeds (10). The primary
metabolic route is hydroxylation followed by conjugation
to glucose. In imidazolinone-resistant crops, the primary
mechanism of selectivity is due to an altered acetolactate
synthase that is not inhibited by imazamox (11).
Animal Metabolism. Metabolism studies in the rat
showed that imazamox is rapidly excreted in the urine.
There was no accumulation of imazamox or any of its
derivatives in the liver, kidney, muscle, fat, or blood (9).
Toxicity evaluation
Imazamox has shown no mutagenic or genotoxic activity in the Ames assay, mammalian cell gene mutation assay, in vitro chromosome aberration assay, in vitro unscheduled DNA synthesis (URS) assay, or the in vivo dominant lethal assay inmale rats. The acute toxicity and effects on wildlife and soilmicroflora of imazamox are shown in Table 4. This herbicide also has a low potential for bioaccumulation in fish.
Imazamox Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Imazamox manufacturers
- Product
- Imazamox 114311-32-9
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 99.99%
- Supply Ability
- 20 tons
- Release date
- 2024-04-10
- Product
- Imazamox 114311-32-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KG
- Release date
- 2018-08-12
- Product
- Imazamox 114311-32-9
- Price
- US $20.00-10.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 20
- Release date
- 2024-04-25