ChemicalBook > CAS DataBase List > CDC801
CDC801
- Product Name
- CDC801
- CAS No.
- 192819-27-5
- Chemical Name
- CDC801
- Synonyms
- CDC801;CDC801, 10 mM in DMSO;3-(3-cyclopentyloxy-4-methoxyphenyl)-3-(1,3-dioxoisoindol-2-yl)propanamide;2H-Isoindole-2-propanamide, β-[3-(cyclopentyloxy)-4-methoxyphenyl]-1,3-dihydro-1,3-dioxo-
- CBNumber
- CB63339637
- Molecular Formula
- C23H24N2O5
- Formula Weight
- 408.45
- MOL File
- 192819-27-5.mol
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CDC801 Property
- Melting point:
- 165-166 °C
- Boiling point:
- 639.7±55.0 °C(Predicted)
- Density
- 1.325±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 16.06±0.40(Predicted)
- color
- White to off-white
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CDC801 Chemical Properties,Usage,Production
Uses
CDC801 is a potent and orally active phosphodiesterase 4 (PDE4) and tumor necrosis factor-α (TNF-α) inhibitor with IC50 of 1.1 μM and 2.5 μM, respectively.
IC 50
PDE4
References
[1] Man HW, et al. Discovery of (S)-N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4and tumor necrosis factor-alpha inhibitor. J Med Chem. 2009 Mar 26;52(6):1522-4. DOI:10.1021/jm900210d
CDC801 Preparation Products And Raw materials
Raw materials
Preparation Products
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CDC801 Suppliers
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