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CDC801

Product Name
CDC801
CAS No.
192819-27-5
Chemical Name
CDC801
Synonyms
CDC801;CDC801, 10 mM in DMSO;3-(3-cyclopentyloxy-4-methoxyphenyl)-3-(1,3-dioxoisoindol-2-yl)propanamide;2H-Isoindole-2-propanamide, β-[3-(cyclopentyloxy)-4-methoxyphenyl]-1,3-dihydro-1,3-dioxo-
CBNumber
CB63339637
Molecular Formula
C23H24N2O5
Formula Weight
408.45
MOL File
192819-27-5.mol
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CDC801 Property

Melting point:
165-166 °C
Boiling point:
639.7±55.0 °C(Predicted)
Density 
1.325±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
16.06±0.40(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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CDC801 Chemical Properties,Usage,Production

Uses

CDC801 is a potent and orally active phosphodiesterase 4 (PDE4) and tumor necrosis factor-α (TNF-α) inhibitor with IC50 of 1.1 μM and 2.5 μM, respectively.

IC 50

PDE4

References

[1] Man HW, et al. Discovery of (S)-N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4and tumor necrosis factor-alpha inhibitor. J Med Chem. 2009 Mar 26;52(6):1522-4. DOI:10.1021/jm900210d

CDC801 Preparation Products And Raw materials

Raw materials

Preparation Products

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CDC801 Suppliers

MedChemexpress LLC
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021-58955995
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609-228-5909
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sales@medchemexpress.cn
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United States
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ShangHai Caerulum Pharma Discovery Co., Ltd.
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18149758185
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sales-cpd@caerulumpharma.com
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China
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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021-65675885
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info@efebio.com
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China
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
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China
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12306
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Fan De(Beijing) Biotechnology Co., Ltd.
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15911056312
Email
liming@bio-fount.com
Country
China
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9729
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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32435
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Chunchuang (Wuhan) Technology Co., Ltd
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15727060112
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yutianchun2007@126.com
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China
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cjbscvictory
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China
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Hebei Weite Medical Technology Co., Ltd
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13180081292 13180081292
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contact@wetogethermed.com
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China
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Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
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China
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192819-27-5, CDC801Related Search:


  • CDC801
  • 3-(3-cyclopentyloxy-4-methoxyphenyl)-3-(1,3-dioxoisoindol-2-yl)propanamide
  • 2H-Isoindole-2-propanamide, β-[3-(cyclopentyloxy)-4-methoxyphenyl]-1,3-dihydro-1,3-dioxo-
  • CDC801, 10 mM in DMSO
  • 192819-27-5