Coumarin 343 X NHS ester

Product Name: Coumarin 343 X NHS ester
CAS No.: 946123-12-2
Chemical Name: Coumarin 343 X NHS ester
Synonyms: Coumarin 343 X NHS;Coumarin 343 X NHS ester;Hexanoic acid, 6-[[(2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-10-yl)carbonyl]amino]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber: CB63344958
Molecular Formula: C26H29N3O7
Formula Weight: 495.52
MOL File: 946123-12-2.mol

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Coumarin 343 X NHS ester Property

Density: 1.41±0.1 g/cm3(Predicted)
solubility: Soluble in DCM, DMSO, DMF
pka: 12.88±0.20(Predicted)
Appearance: Yellow solid
ex/em: 437/477 nm
ε(extinction coefficient): 39000 L⋅mol−1⋅cm−1
Φ(quantum yield): 0.63
InChI: InChI=1S/C26H29N3O7/c30-20-9-10-21(31)29(20)36-22(32)8-2-1-3-11-27-25(33)19-15-17-14-16-6-4-12-28-13-5-7-18(23(16)28)24(17)35-26(19)34/h14-15H,1-13H2,(H,27,33)
InChIKey: UTYUORAKIFFNAS-UHFFFAOYSA-N
SMILES: C(ON1C(=O)CCC1=O)(=O)CCCCCNC(C1=CC2=CC3=C4C(=C2OC1=O)CCCN4CCC3)=O

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Hazard and Precautionary Statements (GHS)

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Coumarin 343 X NHS ester Chemical Properties,Usage,Production

Description

Blue emitting Coumarin 343 dye can form a FRET pair with fluorescein (FAM). An amine reactive form, activated NHS ester._x000D_ This amine-reactive NHS ester contains an aminohexanoyl linker between the fluorophore, and the reactive group. This linker provides better solubility and spatial separation between the fluorophore, and the target molecule being labeled.

Chemical Properties

Appearance: Yellow solid
ex/em: 437/477 nm
Extinction coefficient (ε): 39000 L??mol??1??cm??1
Quantum yield (Φ): 0.63

Uses

Coumarin 343 X NHS ester is a homologue of Coumarin 343 (HY-W267364). Coumarin 343 is a hydrophilic fluorescent probe for use in microfluids.

Abs/Em Maxima

437/477 nm

Fluoresene quantum yield

0.63

Extinction Coefficient

39000

CF260

0.29

CF280

0.24

Coumarin 343 X NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Coumarin 343 X NHS ester Suppliers

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946123-12-2, Coumarin 343 X NHS esterRelated Search:

Coumarin 343 azide ATTO 390 NHS ESTER AMCA-NHS

Coumarin 343 X NHS ester

Hexanoic acid, 6-[[(2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-10-yl)carbonyl]amino]-, 2,5-dioxo-1-pyrrolidinyl ester

Coumarin 343 X NHS

946123-12-2