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Cyanine5 azide

Product Name
Cyanine5 azide
CAS No.
1267539-32-1
Chemical Name
Cyanine5 azide
Synonyms
Cyanine5 azide;lipo Cy5(Me) N3;lipo Cy5(Me) azide;Cyanine5 azide (DMSO solution)
CBNumber
CB63344983
Molecular Formula
C35H45ClN6O
Formula Weight
601.24
MOL File
1267539-32-1.mol
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Cyanine5 azide Property

solubility 
Soluble in DMSO, DMF, DCM
form 
Solid
color 
Light brown to brown
Appearance
Dark blue solid
ex/em
640/664 nm (PBS buffer)
ε(extinction coefficient)
250000 L⋅mol−1⋅cm−1
Φ(quantum yield)
0.2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23908
Product name
Cy5Azide
Purity
98%
Packaging
25mg
Price
$400
Updated
2021/12/16
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Cyanine5 azide Chemical Properties,Usage,Production

Description

Cy5 azide is a reactive dye containing an azide group which can participate in Click-Chemistry reactions. Cyanine5 is suitable for many different methods of fluorescence detection and can be easily detected in small quantities (nM) by naked human eye.

Chemical Properties

Appearance: Dark blue solid
ex/em: 640/664 nm (PBS buffer)
Extinction coefficient (ε): 250000 L??mol??1??cm??1
Quantum yield (Φ): 0.2

Uses

Cyanine5 azide chloride is a potent fluorescent dye. Cyanine5 azide chloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm)[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

References

[1] Huppelschoten Y, et, al. Total Chemical Synthesis of a Functionalized GFP Nanobody. Chembiochem. 2022 Aug 3:e202200304. DOI:10.1002/cbic.202200304

Abs/Em Maxima

646/662 nm

Fluoresene quantum yield

0.2

Extinction Coefficient

250000

CF260

0.03

CF280

0.04

Cyanine5 azide Preparation Products And Raw materials

Raw materials

Preparation Products

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Cyanine5 azide Suppliers

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1267539-32-1, Cyanine5 azideRelated Search:


  • Cyanine5 azide
  • lipo Cy5(Me) azide
  • lipo Cy5(Me) N3
  • Cyanine5 azide (DMSO solution)
  • 1267539-32-1