Cyanine5.5 hydrazide
- Product Name
- Cyanine5.5 hydrazide
- CAS No.
- 2280971-80-2
- Chemical Name
- Cyanine5.5 hydrazide
- Synonyms
- Cyanine5.5 hydrazide;Sulfo-Cyanine5.5 hydrazide;Cyanine5.5 hydrazide,Cy5.5 hydrazide
- CBNumber
- CB83344992
- Molecular Formula
- C40H45N4O+
- Formula Weight
- 597.83
- MOL File
- 2280971-80-2.mol
Cyanine5.5 hydrazide Property
- solubility
- practically insoluble in water (< 2 uM), good in polar organic solvents (DMF, DMSO, alcohols)
- Appearance
- dark blue powder
Cyanine5.5 hydrazide Chemical Properties,Usage,Production
Description
Cyanine5.5 hydrazide is a carbonyl-reactive near infrared dye. Hydrazides quickly react with carbonyl compounds, such as aldehydes and ketones, and form stable hydrazones. This reaction is useful for the preparation of labeled conjugates.
Carbonyl groups in biomolecules can form spontaneously after oxidative stress or deamination of proteins. Alternatively, aldehyde groups can be specifically generated by periodate oxidation of sugar residues of glycoproteins, for example antibodies. Antibodies can be oxidized by sodium periodate and labeled with Cyanine5.5 hydrazide to form Cyanine5.5 labeled antibodies. Since sugar residues in antibodies are located far from variable, epitope-binding site, this method is particularly good for the labeling of antibodies.
Cyanine5.5 is a near infrared fluorophore, an analog of Cy5.5®. It is particularly suitable for the applications which require low fluorescence background. The absorption and emission wavelength of the dye exhibit significant tissue penetration, so Cyanine5.5 is suitable for in vivo NIR imaging applications.
Abs/Em Maxima
684/710 nm
Fluoresene quantum yield
0.2
Extinction Coefficient
198000
CF260
0.07
CF280
0.03
Cyanine5.5 hydrazide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Cyanine5.5 hydrazide manufacturers
- Product
- Cyanine5.5 hydrazide 2280971-80-2
- Price
- US $0.00/mg
- Min. Order
- 25mg
- Purity
- >99.00%
- Supply Ability
- 25mg
- Release date
- 2024-03-29