Cyanine5 azide
- Product Name
- Cyanine5 azide
- CAS No.
- 1267539-32-1
- Chemical Name
- Cyanine5 azide
- Synonyms
- Cyanine5 azide;lipo Cy5(Me) N3;lipo Cy5(Me) azide;Cyanine5 azide (DMSO solution)
- CBNumber
- CB63344983
- Molecular Formula
- C35H45ClN6O
- Formula Weight
- 601.24
- MOL File
- 1267539-32-1.mol
Cyanine5 azide Property
- solubility
- Soluble in DMSO, DMF, DCM
- form
- Solid
- color
- Light brown to brown
- Appearance
- Dark blue solid
- ex/em
- 640/664 nm (PBS buffer)
- ε(extinction coefficient)
- 250000 L⋅mol−1⋅cm−1
- Φ(quantum yield)
- 0.2
N-Bromosuccinimide Price
- Product number
- BP-23908
- Product name
- Cy5Azide
- Purity
- 98%
- Packaging
- 25mg
- Price
- $400
- Updated
- 2021/12/16
Cyanine5 azide Chemical Properties,Usage,Production
Description
Cy5 azide is a reactive dye containing an azide group which can participate in Click-Chemistry reactions. Cyanine5 is suitable for many different methods of fluorescence detection and can be easily detected in small quantities (nM) by naked human eye.
Chemical Properties
Appearance: Dark blue solid
ex/em: 640/664 nm (PBS buffer)
Extinction coefficient (ε): 250000 L??mol??1??cm??1
Quantum yield (Φ): 0.2
Uses
Cyanine5 azide chloride is a potent fluorescent dye. Cyanine5 azide chloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm)[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
References
[1] Huppelschoten Y, et, al. Total Chemical Synthesis of a Functionalized GFP Nanobody. Chembiochem. 2022 Aug 3:e202200304. DOI:10.1002/cbic.202200304
Abs/Em Maxima
646/662 nm
Fluoresene quantum yield
0.2
Extinction Coefficient
250000
CF260
0.03
CF280
0.04
Cyanine5 azide Preparation Products And Raw materials
Raw materials
Preparation Products
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