Argatroban Impurity 23
- Product Name
- Argatroban Impurity 23
- CAS No.
- 1356847-56-7
- Chemical Name
- Argatroban Impurity 23
- Synonyms
- [2H3]-Argatroban;Argatroban-d3 (hydrochloride);Argatroban-d3 (Mixture Of Diastereomers)
- CBNumber
- CB63359002
- Molecular Formula
- C23H33D3N6O5S
- Formula Weight
- 511.652625334
- MOL File
- 1356847-56-7.mol
Argatroban Impurity 23 Property
- storage temp.
- Store at -20°C
- solubility
- DMF: soluble,DMSO: soluble,Methanol: soluble
- form
- A solid
N-Bromosuccinimide Price
- Product number
- 25757
- Product name
- Argatroban-d3 (hydrochloride)
- Packaging
- 1mg
- Price
- $299
- Updated
- 2024/03/01
- Product number
- 25757
- Product name
- Argatroban-d3 (hydrochloride)
- Packaging
- 5mg
- Price
- $1340
- Updated
- 2024/03/01
- Product number
- A769002
- Product name
- Argatroban-d3
- Packaging
- 10mg
- Price
- $1980
- Updated
- 2021/12/16
Argatroban Impurity 23 Chemical Properties,Usage,Production
Description
Argatroban-d3 is intended for use as an internal standard for the quantification of argatroban by GC- or LC-MS. Argatroban is a reversible inhibitor of thrombin (IC50s = 0.01 and 0.09 μM for the free and clot-bound forms, respectively). It is selective for thrombin over factor Xa, trypsin, plasmin, and tissue plasminogen activator (Kis = 0.0045, 53, 0.19, 25.7, and 87.7 μM, respectively). It inhibits thrombin-induced platelet aggregation in washed isolated guinea pig platelets with an IC50 value of 0.077 μM. Argatroban (3.2 mg/kg, s.c.) decreases thrombus formation in a guinea pig model of iron chloride-induced arterial thrombosis. Formulations containing argatroban have been used in the prevention or treatment of thrombosis in patients with heparin-induced thrombocytopenia.
Uses
Labelled synthetic thrombin inhibitor. Antithrombotic.
Argatroban Impurity 23 Preparation Products And Raw materials
Raw materials
Preparation Products
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