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Argatroban Impurity 23

Product Name
Argatroban Impurity 23
CAS No.
1356847-56-7
Chemical Name
Argatroban Impurity 23
Synonyms
[2H3]-Argatroban;Argatroban-d3 (hydrochloride);Argatroban-d3 (Mixture Of Diastereomers)
CBNumber
CB63359002
Molecular Formula
C23H33D3N6O5S
Formula Weight
511.652625334
MOL File
1356847-56-7.mol
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Argatroban Impurity 23 Property

storage temp. 
Store at -20°C
solubility 
DMF: soluble,DMSO: soluble,Methanol: soluble
form 
A solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
25757
Product name
Argatroban-d3 (hydrochloride)
Packaging
1mg
Price
$299
Updated
2024/03/01
Cayman Chemical
Product number
25757
Product name
Argatroban-d3 (hydrochloride)
Packaging
5mg
Price
$1340
Updated
2024/03/01
TRC
Product number
A769002
Product name
Argatroban-d3
Packaging
10mg
Price
$1980
Updated
2021/12/16
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Argatroban Impurity 23 Chemical Properties,Usage,Production

Description

Argatroban-d3 is intended for use as an internal standard for the quantification of argatroban by GC- or LC-MS. Argatroban is a reversible inhibitor of thrombin (IC50s = 0.01 and 0.09 μM for the free and clot-bound forms, respectively). It is selective for thrombin over factor Xa, trypsin, plasmin, and tissue plasminogen activator (Kis = 0.0045, 53, 0.19, 25.7, and 87.7 μM, respectively). It inhibits thrombin-induced platelet aggregation in washed isolated guinea pig platelets with an IC50 value of 0.077 μM. Argatroban (3.2 mg/kg, s.c.) decreases thrombus formation in a guinea pig model of iron chloride-induced arterial thrombosis. Formulations containing argatroban have been used in the prevention or treatment of thrombosis in patients with heparin-induced thrombocytopenia.

Uses

Labelled synthetic thrombin inhibitor. Antithrombotic.

Argatroban Impurity 23 Preparation Products And Raw materials

Raw materials

Preparation Products

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Argatroban Impurity 23 Suppliers

Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10413
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6618
Advantage
81