Sitagliptin Impurity 10

Product Name: Sitagliptin Impurity 10
CAS No.: 1253056-01-7
Chemical Name: Sitagliptin Impurity 10
Synonyms: Sitagliptin-8;3-Hydroxy Sitagliptin;Sitagliptin Impurity 09;Sitagliptin phosphate impurity 6;Sitagliptin Hydroxy Amide Impurity;1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluo;1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone;1-Butanone, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-;3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo [4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one;(R/S)-3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
CBNumber: CB63360062
Molecular Formula: C16H14F6N4O2
Formula Weight: 408.3
MOL File: 1253056-01-7.mol

More

Less

Sitagliptin Impurity 10 Property

Boiling point:: 542.2±60.0 °C(Predicted)
Density: 1.61±0.1 g/cm3(Predicted)
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 13.69±0.20(Predicted)
color: White to Off-White

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

Sitagliptin Impurity 10 Chemical Properties,Usage,Production

Uses

1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985), which is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Sitagliptin Impurity 10 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Sitagliptin Impurity 10 Suppliers

China 34 India 3 United States 3 Global 40

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14059
Advantage: 65

Standardpharm Co. Ltd.

Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Country: United States
ProdList: 14336
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81215950 4000-868-328
Email: customer@uwalab.com
Country: United States
ProdList: 10413
Advantage: 58

1253056-01-7, Sitagliptin Impurity 10Related Search:

Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate 2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Sitagliptin Impurity 34 2,4,5-TRIFLUOROBENZYL CHLORIDE (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,Methylester,(bR)- Sitagliptin Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate P,P′-Bis[[(5R)-3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl] (diphosphate) Cabozantinib Impurity F Tedizolid Impurity 3 Cabozantinib impurity A ButanaMide, 4-hydroxy-N-(1-Methylethyl)- (S)-1-Boc-3-hydroxypiperidine ethambutol hydrochloride Docetaxel Impurity 24 Cabozantinib impurity D

Sitagliptin-8

Sitagliptin Hydroxy Amide Impurity

Sitagliptin impurity 41/Sitagliptin Hydroxy Amide Impurity/3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo [4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one

3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo [4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one

1-Butanone, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-

(R/S)-3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one

1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluo

Sitagliptin phosphate impurity 6

Sitagliptin Impurity 09

3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one? (Sitagliptin Impurity）

3-Hydroxy Sitagliptin

1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone

1253056-01-7