CB-1158

Product Name: CB-1158
CAS No.: 2095732-06-0
Chemical Name: CB-1158
Synonyms: INCB01158;Numidargistat;Numidargistat (CB1158, INCB01158);Numidargistat 2HCl (CB1158, INCB01158);(3R,4S)-1-(L-alanyl)-3-amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid;3-Pyrrolidinecarboxylic acid, 3-amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-, (3R,4S)-;(3R,4S)-3-Amino-1-[(2S)-2-aminopropanoyl]-4-[3-(dihydroxyboranyl)propyl]pyrrolidine-3-carboxylic acid
CBNumber: CB63364611
Molecular Formula: C11H22BN3O5
Formula Weight: 287.12
MOL File: 2095732-06-0.mol

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CB-1158 Property

Boiling point:: 574.1±60.0 °C(Predicted)
Density: 1.299±0.06 g/cm3(Predicted)
pka: 2.13±0.40(Predicted)
form: Solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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CB-1158 Chemical Properties,Usage,Production

Uses

(3R,4S)-3-Amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-3-pyrrolidinecarboxylic Acid Dihydrochloride is a salt analog of (3R,4S)-3-Amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-3-pyrrolidinecarboxylic Acid (CAS# 2095732-06-0), which inhibits arginase 1 (Arg1) enzyme and blocks myeloid cell-??mediated immune suppression in the tumor microenvironment.

CB-1158 Preparation Products And Raw materials

Raw materials

Preparation Products

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CB-1158 Suppliers

China 24 United States 5 Global 29

TargetMol Chemicals Inc.

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InvivoChem

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TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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Aladdin Scientific

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2095732-06-0, CB-1158Related Search:

(3R,4S)-1-(L-alanyl)-3-amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid

INCB01158

3-Pyrrolidinecarboxylic acid, 3-amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-, (3R,4S)-

Numidargistat (CB1158, INCB01158)

Numidargistat 2HCl (CB1158, INCB01158)

Numidargistat

(3R,4S)-3-Amino-1-[(2S)-2-aminopropanoyl]-4-[3-(dihydroxyboranyl)propyl]pyrrolidine-3-carboxylic acid

2095732-06-0

C11H22BN3O5

pyrolidine